Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharm > Antidepressants > Flashcards

Antidepressants Flashcards

1
Q

In general, what is the MOA of antidepressants?

A

Modulate Serotonin, NE, Dopamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

General SE

A

Anticholinergic (dry), dizziness, increased threshold for seizures, HA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Black box warning?

A

Increased risk of suicide esp <25yo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

5 types of antidepressants

A 
MAO inhibitors
TCA
TeCA
SSRI
SNRI
NDRI
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is contraindicated to consume while taking MAO inhibitors?

A

Tyramine containing foods because can’t breakdown and will cause increased NE leading to HTN, HA, Nausea

Raisins, red wine, meat, cheese NOT CHEESE :(

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the TCA Antidepressant?

A

Amitriptyline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What hormone(s) does the TCA drug effect?

A

Serotonin, NE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

How to dose Amitriptyline?

A

PO, at bedtime, as needed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Bummer side of Amitriptyline toxicity?

A

Increase QT wave

=arrhythmias

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Which is the TeCA drug?

A

Trazadone (4 rings instead of 3)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Which is safer? Amitriptyline or Trazadone?

A

Trazadone but watch for hypOtension

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What hormone does Trazadone work on?

A

Serotonin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is the most common antidepressant given?

A

SSRIs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the SSRI drug?

A

Prozac

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

How long does it take for Prozac to work?

A

6-8w

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What should you not take w Prozac and why?

A

NSAIDS: Increases peristalsis and GI bleeds

17
Q

Two major SE of Prozac, besides the general ones for all other antidepressants?

A

Serotonin Syndrome

Decreased sexual function

18
Q

What is the SNRI drug?

A

Cymbalta

19
Q

What two random conditions does Cymbalta tx?

A 
Peripheral neuropathy (think diabetics)
Fibromyalgia
20
Q

What pt population should you not use Cymbalta on?

A

Alcoholics = more seizures

Chronic liver disease

21
Q

What is the NDRI drug?

A

Wellbutrin/Zyban

22
Q

Dosing of Zyban?

A

150mg one a day for 3 days then 150mg BID for 9ish weeks

23
Q

How long does it take for Zyban to reach target blood levels?

A

5-7 days

24
Q

Zyban is helpful for?

A

Smoking cessation

25
Q

What nutrient is helpful with depression?

A

Folic Acid

26
Q

What is the dosing for Levomefolic acid?

A

7.5 & 15mg

Pharm (5 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions