Antidepressants and Antiepileptics Flashcards Preview

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Flashcards in Antidepressants and Antiepileptics Deck (11)
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1
Q

Action of antidepressants

A

Delaying NT reuptake

Inhibiting MAO action

2
Q

Neurotransmitter reuptake inhibitors

A

Tricyclic antidepressants
SSRI (Selective serotonin reuptake inhibitors)
Other antidepressants (Venlafaxine)

3
Q

Tricyclic antidepressants indications

A
Antidepressant
Nocturnal pain
Nocturnal enuresis (pipi)
Anorexia
Migraine prophylaxis
4
Q

SSRI indications

A

First choice antidepressant (bc less ADRs than 3c ad)

Bulimia

5
Q

MAO isoenzymes

A

MAO A:
More in intestine, unfolds selectively serotonin and noradrenaline
MAO B:
More in brain acts on the metabolism of dopamine

6
Q

Epilepsy cause

A

Abnormal excessive and hypersynchronous neuronal activity.

Disproportionate temporary neuronal discharge

7
Q

Classification of seizures; Generalized

A
  • Absence seizures (petit mal) brief loss of consciousness no motor movements immobile person
  • Tonic-clonic seizures (grand mal) sudden loss of consciousness tonic contraction of all the muscles
  • “status epilepticus” Repetition of seizures without recovery of consciousness
8
Q

Classification of seizures; Partial

A
  1. Simple partial seizures:
    No loss of consciousness
    -Motor : mvmts of a member
    -Sensitive: sensory disturbances (auditive and visual)
    -Psychic: cognitive disorders (Hallucinations, delusion)
  2. Complex partial seizures:
    Decreased level of consciousness apprears awake but unresponsive. Repetitive automatic mvmts.
9
Q

Drug to eliminate seizures

A

Diazepam (Valium)

10
Q

2nd generation antiepileptic drugs

A

Gabapentin

Pregabalin

11
Q

Gingival hyperplasia treatment

A

Phenytoin