Antidysrhythmic, cholesterol, angina drugs

Question 1

Classes of antidysrhythmic drugs

Answer 1

Class Ia, Ib, Ic - sodium channel blockers
Class II - Beta blockers
Class III - potassium channel blockers
Class IV - calcium channel blockers

Question 2

All antidysrhythmic drugs can

Answer 2

worsen an existing dysrhythmia or cause a new one

Question 3

Lidocaine route

Answer 3

IV only

Question 4

Lidocain class

Answer 4

sodium channel blocker

Question 5

Lidocaine use

Answer 5

ventricular dysrhythmias, sustained ventricular tachycardia

Question 6

Lidocaine MOA

Answer 6

blocks sodium channels
- slowed conduction

Question 7

Lidocaine adverse effects

Answer 7

CNS - drowsy, confusion, paresthesia
Tingling, burning

Question 8

Lidocaine interactions

Answer 8

digoxin

Question 9

Lidocaine implications

Answer 9

• equipment for resuscitation must be available
• reduce dose in patient with impaired liver or renal blood flow

Question 10

Amiodarone class

Answer 10

potassium channel blocker

Question 11

Amiodarone route

Answer 11

PO, IV

Question 12

Amiodarone use

Answer 12

only approved for life threatening ventricular dysrhythmias

Question 13

Amiodarone MOA

Answer 13

blocks cardiac potassium channels
- delay heart repol
- prolong QT interval

Question 14

Amiodarone interactions

Answer 14

• grapefruit juice
• diuretics: dysrhythmias
• BB, CCBs: cause bradycardia
• increases levels of other drugs

Question 15

Amiodarone adverse effects

Answer 15

• pulmonary toxicity (pneumonitis, pulm fibrosis)
• visual damage
• cardiotoxicity: bradycardia
• thyroid toxicity
• hepatotoxic
• photosensitivity
• teratogenic
• n/v, anorexia

Question 16

Amiodarone implications

Answer 16

• long half life (25-110 days)
• monitor TSH, liver
• monitor for pulm toxicity (wheezing, tachypnea, crackles, SOB, cough)

Question 17

Verapamil, Diltiazem class

Answer 17

calcium channel blockers

Question 18

Verapamil, diltiazem use

Answer 18

atrial fibrillation, atrial flutter, SVT

Question 19

Verapamil, diltiazem MOA

Answer 19

blocks cardiac calcium channels

Question 20

Verapamil, diltiazem adverse effects

Answer 20

constipation, peripheral edema, bradycardia, AV block, hypotension, HF

Question 21

Verapamil, diltiazem interactions

Answer 21

digoxin - elevates levels
combining with BB can cause bradycardia, AV block, HF

Question 22

Verapamil, diltiazem implications

Answer 22

• monitor BP and HR w/BB
• monitor digoxin w/CCC

Question 23

Propranolol Class

Answer 23

BB

Question 24

Propranolol Use

Answer 24

atrial fibrillation, sinus tachycardia, SVT

Question 25

Propranolol MOA

Answer 25

blocks actions of beta receptors - decrease BP and CO

Question 26

Propranolol adverse effects

Answer 26

heart block, worsen HF, sinus arrest, hypotension, bronchospasm

Question 27

Propranolol implications

Answer 27

- monitor BP and HR w/BB - caution asthmatic/COPD - contraindicated w/ sinus bradycardia, high degree heart block, HF

Question 28

Digoxin route

Answer 28

PO, IV

Question 29

Digoxin Use

Answer 29

CHF, supraventricular dysrhythmias

Question 30

Digoxin MOA

Answer 30

slows conduction time through AV node

Question 31

Digoxin adverse effects

Answer 31

dysrhythmias, n/v, anorexia, abdomen discomfort, visual disturbances

Question 32

Digoxin implications

Answer 32

monitor potassium while taking digoxin