Antiemetics

Question 1

Blocks post synaptic dopamine receptors in chemoreceptor trigger zone
-Don’t use w/ severe CNS depression

Answer 1

Compazine

Question 2

Blocks domanine in CTZ

Increases GI motility and gastric emptying w/o increasing secretions

Answer 2

Metoclopramide

Question 3

5-HT3 receptor antagonist–>blocks seratonin at vegus nerve and in CTZ

Answer 3

Ondansetron

Question 4

Reduces stimuli to brainstem.

Blocks Ach

Answer 4

Promethazine