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Flashcards in antifungal drugs Deck (9)
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1

What are the indication for Anti-Fungal Meds?

To treat fungal infections, such as athlete's foot, ringworm, candidiasis (thrush), serious systemic infections such as cryptococcoal meningitis

2

What are the 3 classes of Antifungals

Polyene, Pyrimidine, and Azole Intravenous

3

What is an example of a drug from Polyene?

Amphotericin B (Generic) and Fungizone (Brand) - Normally given in IV or Oral solution

4

What is an example of Pyrimidine?

Flucytosine (Generic) and Ancoban ( Brand) Oral tablet

5

What is an example of Azole Intravenous?

Fluconazole (generic) and Diflucan (brand) - oral tablet & oral suspension

6

Method of action for Azole?

Interfere with the biosynthesis of ergosterol, which is essential for fungal cell membranes and impairs their growth

7

Method of action for Polyene?

It binds to ergosterol in fungal cell membranes, causing them to become permeable or leaky..

8

Method of action for Pyrimadine/ Flucytosine?

Inhibits the dna and rna synthesis in the pathogen

9

What are the side effects of anti-fungal drugs?

Anaphylaxis, hives, itching, swelling, breathing/ swallowing problems, sudden drop in BP, diarrhea, abdominla pain