antifungal drugs Flashcards Preview

Patho Quiz 2 > antifungal drugs > Flashcards

Flashcards in antifungal drugs Deck (9)
Loading flashcards...

What are the indication for Anti-Fungal Meds?

To treat fungal infections, such as athlete's foot, ringworm, candidiasis (thrush), serious systemic infections such as cryptococcoal meningitis


What are the 3 classes of Antifungals

Polyene, Pyrimidine, and Azole Intravenous


What is an example of a drug from Polyene?

Amphotericin B (Generic) and Fungizone (Brand) - Normally given in IV or Oral solution


What is an example of Pyrimidine?

Flucytosine (Generic) and Ancoban ( Brand) Oral tablet


What is an example of Azole Intravenous?

Fluconazole (generic) and Diflucan (brand) - oral tablet & oral suspension


Method of action for Azole?

Interfere with the biosynthesis of ergosterol, which is essential for fungal cell membranes and impairs their growth


Method of action for Polyene?

It binds to ergosterol in fungal cell membranes, causing them to become permeable or leaky..


Method of action for Pyrimadine/ Flucytosine?

Inhibits the dna and rna synthesis in the pathogen


What are the side effects of anti-fungal drugs?

Anaphylaxis, hives, itching, swelling, breathing/ swallowing problems, sudden drop in BP, diarrhea, abdominla pain