Antifúngicos alilaminas Flashcards

1
Q

Alilaminas incluyen

A

terbinafina

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2
Q

Mecanismo de acción de terbinafina/alilaminas

A

bloquean la sintesis de ergosterol al inhibir la escualeno epoxidasa
alteran la permeabilidad de la membrana -> causa roturas

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3
Q

Administracion de terbinafina/alilamina?

A

topica y oral

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4
Q

RAM de terbinafina/alilamina?

A

bien tolerado

  • molestias gastrointestinales
  • reacciones alergicas cutaneas
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5
Q

espectro de terbinafina/alilamina

A

cándida y dermatofitos

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6
Q

Apl.ter. de terbinafina/alilamina?

A
dermatomicosis (tiñas) y candidasis
micosis superficiales (no tienen eficaz para micosis sisémicas)
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