Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Cam's Cards COPY > Antihistamines > Flashcards

Antihistamines Flashcards

1
Q

What is the effect of histamine on blood vessels?

A

Vasodilation (causing hypotension and nasal congestion) and increased permeability (angioedema)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the effect of histamine on bronchiolar smooth muscle?

A

Bronchocontriction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the effect of histamine on neurons?

A

Stimulation of sensory nerve endings causing pain and itching

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Function of histamines on the GI tract?

A

Contraction of smooth muscle(Cramping) and increase in gastric acid secretion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the types of histamine receptors?

A

H1 and H2

H1 does everything except increase gastric acid secretion.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

1st generation antihistamines block what histamine receptors?

A

H1 receptors and H2 receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

2nd generation antihistamines block what histamine receptors?

A

Relatively selective for H1 receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

T/F? 1st generation and second generation antihistamines have equal efficacy in blocking H1 receptors?

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What blocking actions are preformed by antihistamines?

A

H1 receptor block
Muscarinic receptor block
Sodium channel blockade
Adrenergic (alpha 1) receptor block

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What generation of antihistamines cause lower levels of sedation?

A

2nd generation antihistamines

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Clinical uses of 1st generation antihistamines?

A

Cough suppression
Motion sickness
Nausea-vomiting of pregnancy
Sleep aid for insomnia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Mechanism of cough suppression of antihistamines?

A

Na+ channel block

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Mechanism of motion sickness suppression of antihistamines?

A

H1 and M receptor block

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Mechanism of nausea/vomiting suppression of antihistamines?

A

H1 and M receptor block

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Mechanism of sleep aid of antihistamines?

A

H1 and M receptor block

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Why do first generation side effects cause drowsiness?

A

Increased CNS penetration

17
Q

What are the first generation antihistamines?

A 
Chlorpheniramine
Diphenhydramine
Dimenhydrinate
Hydroxyzine
Meclizine
Promethazine
18
Q

What are the second generation antihistamines?

A

Cetirizine
Fexofenadine
Loratadine

19
Q

Intranasal antihistamines?

A

Azelastine

Cam's Cards COPY (93 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions