Antimicrobial Agents Flashcards Preview

Laura Path Recall > Antimicrobial Agents > Flashcards

Flashcards in Antimicrobial Agents Deck (43):
1

Antibiotic vs. skin infection (Staph Aureus)

Flucloxacillin

2

Antibiotic vs. CAP (mild)

Amoxicillin (or macrolide if pen allergic)

3

Antibiotic vs. CAP (severe) (x2)

Co-amoxiclav and clarithromycin (macrolide)

4

Antibiotic vs. Atypical CAP (x2)

Doxycycline + Clarithromycin

5

Antibiotic vs. Bacterial Meningitis (meningococcus/streptococcus)

Ceftriaxone

6

Antibiotic vs. HAP (x2)

Ciprofloxin + Vancomycin

7

Antibiotic vs. Pharyngitis (B haemolytic Strep)

Benzypenicillin

8

Antibiotic vs. UTI (community aquired)

Trimethoprim/Nitrofuratoin

9

Antibiotic vs. UTI (hospital aquired) (x2)

Co-amoxiclav or Cephalexin

10

Antibiotic vs. Colitis (C. diff)

Metronidazole

11

Antibiotic vs. neutropenic sepsis (x2)

Tazocin and Gentamycin

12

Antibiotic vs. severe sepsis (x3)

Tazocin/ceftriaxone + metronidazole

13

Class of drug: Ceftrioxone

Cephalosporin (B lactams)
Inhibit cell wall synthesis

14

Class of drug: Meropenem

Carbapenem (B lactams)
Inhibit cell wall synthesis

15

What is co-amoxiclav?

Amoxicillin (B lactam abx) and Clavulanic Acid (a B lactamase inhibitor)

16

What is Tazocin?

Tazobactam (B lactamase inhibitor) and Piperacillin (ureidopenicillin - B lactam abx)

17

Class of drug: Gentamicin

Aminoglycoside
Inhibits protein synthesis

18

Class of drug: Doxycycline

Tetracycline
Inhibits protein synthesis

19

Class of drug: Erythomycin

Macrolide
Inhibits protein synthesis

20

Class of drug: Clarithromycin

Macrolide
Inhibits protein synthesis

21

Class of drug: Linezolid

Oxazolidinone
Inhibits protein synthesis

22

Class of drug: Ciprofloxin

Fluoroquinone
Inhibits DNA synthesis

23

Class of drug: Metronidazole

Nitroimidazole
Inhibits DNA synthesis

24

MOA: Rifampacin

Inhibits RNA synthesis

25

Class of drug: Colistin

Polymyxin
Cell membrane toxin

26

Class of drug: Daptomycin

Cyclic lipopeptide
Cell membrane toxin

27

Class of drug: Sulfamethoxazole

Sulphonamide
Inhibits folate metabolism

28

Class of drug: Trimethoprim

Diaminopyrimidine
Inhibits folate metabolism

29

What is co-trimoxazole?

Trimethoprim and sulfamethoxazole

30

Treatment for MRSA?

Vancomycin

31

Treatment for S. Aureus (eg. cellulitis)?

Flucloxacillin

32

Treatment for psudomonas spp?

Tazocin

33

Treatment for Legionella?

Macrolide + Rifampicin

34

What gram stain do Carbapenems treat? (eg. Meropenem)

G -ve

35

Treatment vs. intracellular chlamydia?

Doxycyline (tetracycline)

36

Treatment for G+ve if pen allergic?

Erythromycin (macrolide)

37

Treatment for Bacterial Conjunctivitis

Chloramphenicol eye drops

38

Treatment vs. anaerobes and protozoa?

Metronidazole (Nitroimidazole)

39

Treatment for mycobacteria (TB)?

Rifampacin

40

Treatment for PCP (pneumocystitis jirovecii)

sulfamethoxazole

41

DNA synthesis inhibitors
(1 good vs anaerobes, 1 bad vs anaerobes)

Fluroquinolones (Ciprofloxin) - bad vs. anaerobes
Nitroimidazoles (Metronidazole) - good vs. anaerobes and protozoa

42

B lactam with anti-pseudomonal activity

Piperacillin (part of Tazocin, an extended spectrum penicillin)

43

Broad spec abx, usually given with a B lactamase inhibitor?

Amoxicillin (part of co-amoxiclav with clavulanic acid)