Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

RUSVM Bacteriology > Antimicrobial Drugs > Flashcards

Antimicrobial Drugs Flashcards

(41 cards)

Start Studying
1
Q

Members of the tetracycline group

A

Oxytetracycline

Chlortetracycline

Doxycycline

Minocycline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

T/F: You can mix Aminoglycoside and B-Lactam in the same syringe

A

False

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Anaphylactic reactions (Type I hypersensitivity) can occur when using B-Lacatms because

A

Anaphylactic reactions (Type I hypersensitivity) can occur when using B-Lacatms because Penicillin acts like a hapten

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Lincosamides are bacterio (-static/-cidal)

A

Lincosamides are bacterio (-static/-cidal)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Peptide antibiotics

A

Glycopeptides (Vancomycin)

Polymyxins

Bacitracin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Members of lincosamides group

A

Clindamycin

Lincomycin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

T/F: Aminoglycosides are time dependent antimicrobials

A

False

____________________

Concentration dependent

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

B-Lactams are bacterio (-static/-cidal) antimicrobials

A

B-Lactams are bacterio (-static/-cidal) antimicrobials

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Mechanism of action of chloramphenicol

A

Inhibit protein synthesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Members of the fluoroquinolone family

A

Enrofloxacin

Ciprofloxacin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Members of the aminoglycoside family

A

Gentamicin

Tobramycin

Streptomycin

Kanamycin

Neomycin

Spectinomycin

Amikacin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Aminoglycosides are bacterio (-cidal/-static)

A

Aminoglycosides are bacterio (-cidal/-static)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Sulfa drugs cause allergic reactions in

A

Doberman pinschers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Macrolides are bacterio (-static/-cidal)

A

Macrolides are bacterio (-static/-cidal)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Mechanism of action of lincosamides

A

Inhibit protein synthesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Mechanism of action of Macrolides

A

Inhibit protein synthesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

T/F: Fluoroquinolones are time dependent antimicrobials

Study These Flashcards
A

False; concentration dependent

18
Q

Mechanism of action of B-Lactams

Study These Flashcards
A

Inhibit cell wall synthesis - peptidoglycan synthesis

Stimulate autolysins to degrade peptidoglycan

19
Q

Sulfa drugs are excreted through

Study These Flashcards
A

Bile, feces, urine

20
Q

Ineffective against anaerobes

Study These Flashcards
A

Aminoglycosides

Fluoroquinolones

21
Q

Members of B-Lactam Group

Study These Flashcards
A

Penicillins

Cephalosporins

Sublactams

Carbapenems

Monobactams

22
Q

Rifampin mechanism of action

Study These Flashcards
A

Inhibit RNA polymerase

23
Q

Synergistic combinations of B-Lactams

Study These Flashcards
A

+ B - lactamase inhibitors (Clavulinic Acid)

+ Aminoglycoside - facillitate entry into cell

+ quinolone - pseudomonas infection

24
Q

Toxicity and adverse effects of tetracyclines

Study These Flashcards
A

Irritant

Cardiovascular effects

Tooth discoloration

Alteration of intestinal flora and enterocolitis - horse

IV administration in horse - cardiovascular collapse

Nephrotoxicosis

25
Chloramphenicols are bacterio (-static/-cidal)
Chloramphenicols are bacterio (**-static**/-cidal)
26
Resistance mechanisms of B-Lactams
B-Lactamase - cleaves B lactam ring Extended spectrum B-lacatamase Alteration of penicillin binding proteins
27
Tetracyclines are bacterio (-cidal/-static)
Tetracyclines are bacterio (-cidal/**-static**)
28
T/F: Tetracyclines are time dependant antimicrobials
True
29
Mechanism of action of aminoglycosides
Inhibit protein sythensis
30
Members of the sulfa drug group
Sulfonamide Sulfamethoxazole Sulfadiazine
31
Antagonistic combinations of B-Lacatms
Tetracycline Chlormanphenicol
32
Members of the macrolides group
Erythromycin Azithromycin Clarithromycin
33
Tetracycline is a (broad/narrow) spectrum antimicrobial
Tetracycline is a (**broad**/narrow) spectrum antimicrobial
34
Mechanism of action of Fluoroquinolones
Inhibit DNA gyrase (DNA replication)
35
Chloramphenicol group
Thaimphenicol Florfenicol
36
Resistance mechanisms of tetracyclines
Energy dependent efflux Ribosomal protection Chemical modification and catalysis by enzymes
37
Excretion of B-Lacatams is through the
Excretion of B-Lacatams is through the **kidney**
38
Rifampin is bacterio (-static/-cidal)
Rifampin is bacterio (-static/-**cidal**) \_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_ against intra and extra-cellular bacteria
39
Mechanism of action of Tetracyclines
Inhibit protein synthesis
40
T/F: B-Lactams involve Time Dependant Killing
True
41
Do not combine lincosamides with
Macrolides

RUSVM Bacteriology (21 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions