Antimicrobial Prophylaxis

Question 1

Which antimicrobial is used for surgical prophylaxis?

Answer 1

Cefazolin 2g

Question 2

When should prophylactic antimicrobial agents be adminstered before surgery?

Answer 2

Not more than 30 to 60 before surgery
;
Except for vancomycin and fluoroquinolones should be 90 to 120 min before surgery

Question 3

The duration of antimicrobial prophylaxis shouldnt exceeed ….hr with the exception of cardiac surgeries can be continued up to ….hrs

Answer 3

24hrs
48hrs

Question 4

After how many hours should cefazolin be readministred ?

Answer 4

Again after 4hrs

Question 5

To whom is rheumatic fever prophylaxxy given? What is the drug name?

Answer 5

Ppl with heart diseases

Penicillin G benzathine (1.2 million U IM every 4 week)

Question 6

Prophylaxy for recurrent cellulitis?

Answer 6

Penicillin V
Or
Penicillin G benzathine

Question 7

How is meningococcal disease transmitted?

Answer 7

Contact

Question 8

What is the prophylaxy for meningococcal disease?

Answer 8

• Rifampin 600 mg orally every 12 h for 2 day or,
• Ciprofloxacin 500 mg orally for 1 dose (adults) or,
• Ceftriaxone 250 mg IM once

Question 9

UTI prophylaxy?

Answer 9

Methenamine hippurate (dosage, 1 g twice daily)

Question 10

What are the agents involved in dog and cat bite?

Answer 10

Pasteurella
Staphyloccocus
Streptococcus
Anaerobes

Question 11

Bite wound infection prophylaxy?

Answer 11

Amoxicillin-clavulanate 875 mg orally twice daily for 3-5 day

Question 12

Infective endocarditis prophylaxy especially before dental procedures IN PT WITH CARDIAC ILLNESSES?

Answer 12

Amoxicillin 2g
Or
Ampicillin 2g
Iv or im

Question 13

How is pertussis transmitted?

Answer 13

Droplet

Question 14

What does bordetella pertussis cause

Answer 14

Whooping cough

Question 15

Pertussis prophylaxy?

Answer 15

Azithromycin 500 mg orally day 1, then 250
mg per day on days 2-5

Question 16

Herpes simplex viral infection prophylaxy

Answer 16

Aciclovir 400 mg orally twice daily

Question 17

Pre exposure HIV prophylaxy (before HIV exposure lit party)**

Answer 17

Raltegravir 400 mg twice daily

+
tenofovir (TDF) and
emtricitabine (FTC)

Question 18

Malaria prophylaxy and usage ?

Answer 18

Atovaquone-proguanil
[before travel in 1-2 days and after returning take for 7 days]

Question 19

Prophylaxy for crimean congo hemorrhagic fever?**

Answer 19

Ribavirin 4 x 500 mg/day for 7 days

Question 20

How is crimean congo transmitted?

Answer 20

Ticks-humans
Human-human:body fluids+Close contact