UTI Flashcards

(43 cards)

1
Q

Why is UTI more common in women?

A

Because the urethra is closer to the perianal region

Short urethra

Sexual contact

Adhesion to the epithelium

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2
Q

What is the most common UTI causing organism?

A

Escherichia coli

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3
Q

What does the normal flora of the urethra include?

A

Lactobacilli
Staphylococci

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4
Q

More than —% of cases are caused by a single bacterium?

A

> 95%

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5
Q

What are the bacteria that causes high incidence of UTI in pt with structural urogenital anomalies AND recurrent UTI’s??**

A

Proteus

Pseudomonas

Klebsiella and enterobacter spp.

Enterococci and staphylococci

“P.E.P.SIELLA”

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6
Q

***What is the management for ACUTE CYSTITIS

A

Fosfomycin trometamol

Nitrofurantoin

Trimethoprim-sulphamethoxazole

Fluoroquinolones

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7
Q

List 6 facts about staphylococcus saprophyticus?

A

Gram +

Coagulase -ve

Causes infection in sexually active young women

Reaches the kidney by hematogenous route

Causes intra-renal perirenal abscess

5-15% of acute cystitis

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8
Q

………… microorganisms rarely causes UTI’s

A

Anaerobic

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9
Q

Which microorganism causes UTI in catheterized patients receiving antibiotic therapy

A

Candida(fungi)

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10
Q

Which agent causes HEMORRHAGIC CYSTITIS
in pediatric pt and allogenic bone marrow recipients?

A

Adenovirus

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11
Q

What are the upper UTI?

A

Pyelonephritis
Perinephritic abscess

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12
Q

What are the lower UTI?

A

Urethritis
Cystitis

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13
Q

What is the most common pathogenesis of UTI

A

Ascending pathway; bacteria enter through the urethra and move upwards.

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14
Q

Tru or false: The kidney is frequently affected in patients with Staphylococcus aureus bacteremia or endocarditis.

A

True

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15
Q

***what are the protection mechanisms of UTI?

A

Elimination by voiding

Antibacterial properties of urine

Defense mechanism of bladder mucosa

Acid environment in vagina

Prostate secretion

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16
Q

Risk factors of UTI

A

Urinary obstruction

Catheterization,urethral dilation, cystoscopy

Renal treatment

Vesicoureteral reflux: inc pressure in bladder causes agent to reach kidney

Neurologic: spinal injury and sclerosis(causing dec. bladder emptying)

Dehydration

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17
Q

List 5 risk factors of UTI in females? ***

A

Sexual intercourse

Lack of urination after sex

Spermicidal & Diaphragm

Diabetes m

Pregnancy

Vaginal atrophy/estrogen deficinecy

Pelvic prolapse/cystocele

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18
Q

UTI risk factors in men? ***

A

Uncircumcision

Transfer of Vaginal E.coli while sex

Prostate hypertrophy

Condom catheter

Homosexuah/ rectal intercourse

prostatic enlargement–>obstruction

19
Q

TRUE or FALSE;
SIGNIFICANT BACTERIURIA; Presence of at least 200,000 bacteria per ml in the urine in excess of the possibility of contamination from the anterior urethraà infection

A

False
True 100,000 bacteria

20
Q

Symptoms of cystitis?

A

Frequent urination

Suprapubic pain

Bloody, cloudy urine

Burning

Urgency

21
Q

Which of cystitis or pyelonephritis have prominent CBC values?

A

Pyelonephritis

22
Q

What are the symptoms of pyelonephritis?

A

Dysuria

Pollakiuria(frequent urination)

Urgency

Flank/lower back pain

Fever

23
Q

Which factors cause complicated UTI’s?

A

Urological anomalies

Pregnancy

24
Q

What are the risk factors in COMPLICATED UTI?

A

“ the Male Prostate prevents UTI in Diabetes, PKD, urolithiasis or neurogenic bladder patients”

“In Postmenopausal women who dont get Pregnant have hx of recurrent /childhood UTI’s “

“Hospital-acquired UTI caused by indwelling Catheter, Stents, renal Transplant, Nephrostomy

25
What is the difference between between relaps and reinfection?
RELAPS; Recurrence of bacteriuria with the same causative organism despite treatment REINFECTION; recurrence of infection with a different microorganism - a new infection
26
***what is the criteria for UROSEPSIS/Sepsis Syndrome due to UTI?
2 or more +UTI: 1-temp>38 C or <35 C 2-tachycardia: HR>90b/m 3-RR>20 or PaCO2<32mmHg 4-WBC>12,000 or <4,000 or >10% young form
27
What is the management if pt doesn’t recover after cystitis or pyelonephritis treatment?
CT scan
28
How to sample urine?
1-clean vagina enterance with water-SF (NOT ANTISEPTICS) 2-First morning Midstream urine
29
What is the most accurate indicator of infection in dipstick?
Leukocyte esterase Nitrate PH(less or more than 5.5-6.5)
30
What does a positive leukocyte esterase indicate?
Pyuria(puss in urine)
31
What does a positive nitrate indicate?
Enterobacteria (E.coli, klebsiella, proteus)
32
In which agents does it show negative NITRATE test?
Acinobacter ?pseudomonas aeruginosa Staph saprophyticus Enterococcus spp + Streptococcus spp Staphylococcus spp Mycoplasma spp Nisseria Gonorrhea Hemophilis influenza
33
Which bacteria causes an alkaline pH(by breakiing down urea )
Proteus Providencia Morganella (associated with magnesium ammonium phosphate crystals and stone formation.)
34
***What are the sterile pyuria agents (urethral syndrome=absence of growth in culture in presence of symptoms)?
(Stealth killers) • Chlamydia • Mycoplasma • Ureoplasma • Trichomonas • Gonococci • Candida • Tuberculosis • Stone • Foreign body • Glomerulonephritis
35
Tx for complicated pyelonephritis in pregnants?
Broad spectrum beta lactams
36
Tx for complicated cystitis in pregnants?
Cephalexin or fosfomycin
37
Describe Gonococcal urethritis
Dysuria Sudden onset Spontaneous dysuria and discharge Spontaneous discharge and hyperemia in urethral meatus Incubation 4 days
38
Describe non-Gonococcal urethritis
Either dysuria or discharge Onset within days Long Incubation period (2-23 days) Mucopurulent or serous discharge(whitish-yellow) Spont discharge and hyperemia in urethral meatus
39
** tx for GNC:
Ceftriaxone
40
** tx for NGNC:
Azithromycin Doxycycline
41
****Which are nitrate positive causing uti bacteria?
“Enter the Escheria Klub of Proteus land” 1-enterobacteria 2-E.coli 3-klebsiella 4-proteus
42
A pt comes with purulent dischrage from urethra what is the treatement?
Pt has gonococcal urethritis Tx: ceftriaxone
43
A pt comes with mucopurulent/serous dischrage from urethra what is the treatement?
Pt has non-gonococcal urethritis Tx: azithromycin(1g) or doxycycline(100mg for 7days)