Antimicrobials Flashcards

1
Q

Choose the most appropriate answer from the list.

  • Benzylpenicillin
  • Ceftriaxone
  • Chloramphenicol
  • Clarithromycin
  • Colistin
  • Gentamicin
  • Intravenous
  • Meropenem
  • Moxifloxacin
  • Orally
  • Rifampicin
  • Trimethoprim
  • Vancomycin
  • Rectally

22 year old man presents with a painless, red ulcer on his penis. Microscopy reveals spiral shaped organisms.

A

Benzylpenicillin

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2
Q

Choose the most appropriate answer from the list.

  • Benzylpenicillin
  • Ceftriaxone
  • Chloramphenicol
  • Clarithromycin
  • Colistin
  • Gentamicin
  • Intravenous
  • Meropenem
  • Moxifloxacin
  • Orally
  • Rifampicin
  • Trimethoprim
  • Vancomycin
  • Rectally

On a routine swab for a pre-op patient, the lab is able to culture Staphylococcus aureus. The lab also reports that this particular strain is not sensitive to Penicillins.

A

Vancomycin

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3
Q

Choose the most appropriate answer from the list.

  • Benzylpenicillin
  • Ceftriaxone
  • Chloramphenicol
  • Clarithromycin
  • Colistin
  • Gentamicin
  • Intravenous
  • Meropenem
  • Moxifloxacin
  • Orally
  • Rifampicin
  • Trimethoprim
  • Vancomycin
  • Rectally

The route of administration when administering Vancomycin to treat serious C.difficile infection.

A

Orally

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4
Q

Choose the most appropriate answer from the list.

  • Benzylpenicillin
  • Ceftriaxone
  • Chloramphenicol
  • Clarithromycin
  • Colistin
  • Gentamicin
  • Intravenous
  • Meropenem
  • Moxifloxacin
  • Orally
  • Rifampicin
  • Trimethoprim
  • Vancomycin
  • Rectally

This antibiotic which is usually administered as eye drops, can cause grey baby syndrome in neonates, because of an inability to metabolise the drug.

A

Chloramphenicol

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5
Q

Choose the most appropriate answer from the list.

  • Benzylpenicillin
  • Ceftriaxone
  • Chloramphenicol
  • Clarithromycin
  • Colistin
  • Gentamicin
  • Intravenous
  • Meropenem
  • Moxifloxacin
  • Orally
  • Rifampicin
  • Trimethoprim
  • Vancomycin
  • Rectally

A 21 year old university student presents with meningococcal infection, and he is successfully treated. What prophylaxis might be given to his housemates and closest contacts?

A

Rifampicin

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6
Q

Choose the most appropriate answer from the list.

  • Amoxicillin
  • Metranidazole
  • Ceftriaxone
  • Pyrazinamide
  • Chloramphenicol
  • Rifampicin
  • Ethambutol
  • Vancomycin
  • Erythromycin
  • Flucloxacillin
  • Gentamicin
  • Isoniazid

First line treatment for mild to moderate C. Difficile

A

Metranidazole

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7
Q

Choose the most appropriate answer from the list.

  • Amoxicillin
  • Metranidazole
  • Ceftriaxone
  • Pyrazinamide
  • Chloramphenicol
  • Rifampicin
  • Ethambutol
  • Vancomycin
  • Erythromycin
  • Flucloxacillin
  • Gentamicin
  • Isoniazid

Treatment of infections resistant to penicillin e.g. MRSA

A

Vancomycin

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8
Q

Choose the most appropriate answer from the list.

  • Amoxicillin
  • Metranidazole
  • Ceftriaxone
  • Pyrazinamide
  • Chloramphenicol
  • Rifampicin
  • Ethambutol
  • Vancomycin
  • Erythromycin
  • Flucloxacillin
  • Gentamicin
  • Isoniazid

May cause deafness an unwanted side effect

A

Gentamicin

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9
Q

Choose the most appropriate answer from the list.

  • Amoxicillin
  • Metranidazole
  • Ceftriaxone
  • Pyrazinamide
  • Chloramphenicol
  • Rifampicin
  • Ethambutol
  • Vancomycin
  • Erythromycin
  • Flucloxacillin
  • Gentamicin
  • Isoniazid

20 year old male, with true resistance to penicillin, presents with a severe headache, neck stiffness, fever and photophobia

A

Chloramphenicol

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10
Q

Choose the most appropriate answer from the list.

  • Amoxicillin
  • Metranidazole
  • Ceftriaxone
  • Pyrazinamide
  • Chloramphenicol
  • Rifampicin
  • Ethambutol
  • Vancomycin
  • Erythromycin
  • Flucloxacillin
  • Gentamicin
  • Isoniazid

Treatment of TB but may cause optic neuritis.

A

Ethambutol

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11
Q

Choose the most appropriate answer from the list.

  • Glycopeptides
  • 3 days
  • Cephalexin
  • 7 days
  • Cefotaxime
  • Tazocin
  • Tetracyclines
  • Doxyclycline
  • Macrolides
  • Amoxicillin
  • Cefuroxime
  • Flucloxacillin
  • Beta-lactams
  • Ceftriaxone
  • Aminoglycosides
  • Trimethoprim

Which group of antibiotics is not recommended for use in children or pregnant women?

A

Tetracyclines

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12
Q

Choose the most appropriate answer from the list.

  • Glycopeptides
  • 3 days
  • Cephalexin
  • 7 days
  • Cefotaxime
  • Tazocin
  • Tetracyclines
  • Doxyclycline
  • Macrolides
  • Amoxicillin
  • Cefuroxime
  • Flucloxacillin
  • Beta-lactams
  • Ceftriaxone
  • Aminoglycosides
  • Trimethoprim

Give an example of a second-generation cephalosporin.

A

Cefuroxime

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13
Q

Choose the most appropriate answer from the list.

  • Glycopeptides
  • 3 days
  • Cephalexin
  • 7 days
  • Cefotaxime
  • Tazocin
  • Tetracyclines
  • Doxyclycline
  • Macrolides
  • Amoxicillin
  • Cefuroxime
  • Flucloxacillin
  • Beta-lactams
  • Ceftriaxone
  • Aminoglycosides
  • Trimethoprim

Which group of antibiotics is bacteriostatic and acts on 50S ribosomes to interfere with mRNA translation?

A

Macrolides

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14
Q

Choose the most appropriate answer from the list.

  • Glycopeptides
  • 3 days
  • Cephalexin
  • 7 days
  • Cefotaxime
  • Tazocin
  • Tetracyclines
  • Doxyclycline
  • Macrolides
  • Amoxicillin
  • Cefuroxime
  • Flucloxacillin
  • Beta-lactams
  • Ceftriaxone
  • Aminoglycosides
  • Trimethoprim

A 23-year-old intubated male in ITU developes a chest infection 14 days after admission, which antibiotic would you prescribe?

A

Tazocin

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15
Q

Choose the most appropriate answer from the list.

  • Glycopeptides
  • 3 days
  • Cephalexin
  • 7 days
  • Cefotaxime
  • Tazocin
  • Tetracyclines
  • Doxyclycline
  • Macrolides
  • Amoxicillin
  • Cefuroxime
  • Flucloxacillin
  • Beta-lactams
  • Ceftriaxone
  • Aminoglycosides
  • Trimethoprim

A 28-year-old woman is diagnosed with community-acquired cystitis, what is the recommended duration of antibiotic treatment for this diagnosis?

A

3 days

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16
Q

Choose the most appropriate answer from the list.

  • IV Acyclovir
  • Antiretroviral Therapy
  • Oseltamivir
  • Interferon-alpha and Ribavarin
  • Interferon-beta
  • Symptomatic treatment and reassurance
  • IV Gancyclovir
  • Oral Acyclovir
  • Ribavarin
  • Palivizumab

A 3-week old baby presents with a fever, irritability and painful, vesicular lesions on the tongue, buccal mucosa, lips and face.

A

IV Acyclovir

17
Q

Choose the most appropriate answer from the list.

  • IV Acyclovir
  • Antiretroviral Therapy
  • Oseltamivir
  • Interferon-alpha and Ribavarin
  • Interferon-beta
  • Symptomatic treatment and reassurance
  • IV Gancyclovir
  • Oral Acyclovir
  • Ribavarin
  • Palivizumab

On examination of a newborn child you notice that although they are small their head is unusually out of proportion and seems much smaller than the rest of their body, additionally their skin appears slightly yellow, with a petechial rash.

A

IV Gancyclovir

18
Q

Choose the most appropriate answer from the list.

  • IV Acyclovir
  • Antiretroviral Therapy
  • Oseltamivir
  • Interferon-alpha and Ribavarin
  • Interferon-beta
  • Symptomatic treatment and reassurance
  • IV Gancyclovir
  • Oral Acyclovir
  • Ribavarin
  • Palivizumab

A 2-year old child presents with persistent lymphadenopathy, recurrent fevers and parotid swelling. His adopted parents are unaware of any FH or PMH.

A

Antiretroviral Therapy

19
Q

Choose the most appropriate answer from the list.

  • IV Acyclovir
  • Antiretroviral Therapy
  • Oseltamivir
  • Interferon-alpha and Ribavarin
  • Interferon-beta
  • Symptomatic treatment and reassurance
  • IV Gancyclovir
  • Oral Acyclovir
  • Ribavarin
  • Palivizumab

A primary school teacher brings in her 4-year old child with a fever and an itchy, vesicular rash on his trunk and face.

A

Symptomatic treatment and reassurance

20
Q

Choose the most appropriate answer from the list.

  • IV Acyclovir
  • Antiretroviral Therapy
  • Oseltamivir
  • Interferon-alpha and Ribavarin
  • Interferon-beta
  • Symptomatic treatment and reassurance
  • IV Gancyclovir
  • Oral Acyclovir
  • Ribavarin
  • Palivizumab

An 8-month old child suddenly develops a high fever, headache and a chesty cough. Her mum is concerned as she seems to have lost her appetite over the past 24 hours and is not improving

A

Oseltamivir