Enzymology Flashcards
Choose the most appropriate answer from the list.
- Alanine aminotransferase
- Troponin T
- Aspartate aminotransferase
- BB isoenzyme of CK
- Creatinine phosphokinase
- Cystathionine synthetase
- Lactate dehydrogenase
- MM isoenzyme of CK
- Phenylalanine hydroxylase
An 18 year old male construction worker has a wall collapse on him. The fire department have been trying to release him for the past several hours. He begins to feel nauseous and is constantly retching. Which enzyme will be elevated?
Creatinine phosphokinase
Choose the most appropriate answer from the list.
- Alanine aminotransferase
- Troponin T
- Aspartate aminotransferase
- BB isoenzyme of CK
- Creatinine phosphokinase
- Cystathionine synthetase
- Lactate dehydrogenase
- MM isoenzyme of CK
- Phenylalanine hydroxylase
A 20 year old male with mild mental retardation has had two successive strokes within a year. On examination he had a marfinoid habitus (ie long limbs and pectus excavatum). What is the most likely enzyme defect?
Cystathionine synthetase
Choose the most appropriate answer from the list.
- Alanine aminotransferase
- Troponin T
- Aspartate aminotransferase
- BB isoenzyme of CK
- Creatinine phosphokinase
- Cystathionine synthetase
- Lactate dehydrogenase
- MM isoenzyme of CK
- Phenylalanine hydroxylase
A middle eastern male child with fair complexion adopted a soon after his premature birth is noted to have delayed milestones at 8 months of age. He is also noted to have eczema. At two years of age the child has severe mental retardation with no pyramidal or extra-pyramidal signs. Mental retardation in this child is likely to be due to a defect in which enzyme?
Phenylalanine hydroxylase
Choose the most appropriate answer from the list.
- Alanine aminotransferase
- Troponin T
- Aspartate aminotransferase
- BB isoenzyme of CK
- Creatinine phosphokinase
- Cystathionine synthetase
- Lactate dehydrogenase
- MM isoenzyme of CK
- Phenylalanine hydroxylase
Which enzyme regulated Ca-mediated contractile process of striated muscle and is most specific for minor degrees of myocardial necrosis?
Troponin T
Choose the most appropriate answer from the list.
- Alanine aminotransferase
- Troponin T
- Aspartate aminotransferase
- BB isoenzyme of CK
- Creatinine phosphokinase
- Cystathionine synthetase
- Lactate dehydrogenase
- MM isoenzyme of CK
- Phenylalanine hydroxylase
Which enzyme occurs in high concentration in sarcoplasm of skeletal muscle?
BB isoenzyme of CK
Choose the most appropriate answer from the list.
- Acid phosphatase
- Thyroxine
- Aspartate-amino transferase
- Thyroid peroxidase
- Alanine-amino transferase
- Hypoxanthine-guanine phosphoribosyltransferase
- Alkaline phosphatase
- Urate oxidase
- Gamma-glutamyl transpeptidase
- Glucose-6-phosphate dehydrogenase
- Lactate dehydrogenase
- Thyroglobulin
Autoantibodies against this can be found in the most common form of hypothyroidism
Thyroid peroxidase
Choose the most appropriate answer from the list.
- Acid phosphatase
- Thyroxine
- Aspartate-amino transferase
- Thyroid peroxidase
- Alanine-amino transferase
- Hypoxanthine-guanine phosphoribosyltransferase
- Alkaline phosphatase
- Urate oxidase
- Gamma-glutamyl transpeptidase
- Glucose-6-phosphate dehydrogenase
- Lactate dehydrogenase
- Thyroglobulin
A 79 year old gentleman visits the GP complaining of difficulty passing urine. When asked he also mentioned seeing blood in the urine. What should the GP look for in a blood test?
Acid phosphatase
Choose the most appropriate answer from the list.
- Acid phosphatase
- Thyroxine
- Aspartate-amino transferase
- Thyroid peroxidase
- Alanine-amino transferase
- Hypoxanthine-guanine phosphoribosyltransferase
- Alkaline phosphatase
- Urate oxidase
- Gamma-glutamyl transpeptidase
- Glucose-6-phosphate dehydrogenase
- Lactate dehydrogenase
- Thyroglobulin
This is inhibited by propylthiouracil.
Thyroid peroxidase
Choose the most appropriate answer from the list.
- Acid phosphatase
- Thyroxine
- Aspartate-amino transferase
- Thyroid peroxidase
- Alanine-amino transferase
- Hypoxanthine-guanine phosphoribosyltransferase
- Alkaline phosphatase
- Urate oxidase
- Gamma-glutamyl transpeptidase
- Glucose-6-phosphate dehydrogenase
- Lactate dehydrogenase
- Thyroglobulin
A homeless man who appeared to be quite unkempt and malnourished, was brought into A+E where he appeared to be confused. You notice a strong odour of alcohol. What would you expect to be raised?
Gamma-glutamyl transpeptidase
Choose the most appropriate answer from the list.
- Acid phosphatase
- Thyroxine
- Aspartate-amino transferase
- Thyroid peroxidase
- Alanine-amino transferase
- Hypoxanthine-guanine phosphoribosyltransferase
- Alkaline phosphatase
- Urate oxidase
- Gamma-glutamyl transpeptidase
- Glucose-6-phosphate dehydrogenase
- Lactate dehydrogenase
- Thyroglobulin
A four year old boy is brought into A+E by his carer. He has decreased muscle tone and seems to be fairly irritated and does not seem to speak. You notice several bite marks on his fingers and lips. What is he deficient in?
Hypoxanthine-guanine phosphoribosyltransferase
