Antimicrobials & Vaccines Flashcards by Sophie Coaker

Q

Bacteriostatic

A

Prevents bacteria from reproducing

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Q

Bacteriocidal

A

Kill bacteria

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Q

Examples of common Bacteriostatics

A

Macrolides

Tetracylines

Chloramphenicol

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Q

Examples of Bacteriocidals

A

Beta-lactams

Glycopeptides

Polymyxins

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Q

Fungicide

A

Biocidal chemical used to kill fungi

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Q

Fungistatic

A

Inhibits fungal growth

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Q

Membrane disrupting agents

A

Polyenes

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Q

Ergosterol synthesis inhibitors

A

Azoles, allyamines

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Q

DNA synthesis inhibitor

A

Flucytosine

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Q

Glucan synthesis inhibitors

A

Echinocandins

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Q

Polyenes mode of action

A

Associated with ergosterol to form pore stuctures

Membrane leakage

Cell death (fungicidal)

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Q

How do Azoles inhibit ergosterol synthesis?

A

Inhibits 14(alpha) sterol demethylase

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Q

How do azoles alter membrane fluidity?

A

Build up of 14(alpha) sterols

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Q

What type of antifungal is Azole?

A

Broad spectrum fungistatic

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Q

A

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