Antiplatelets/Anticoagulants

Question 1

Enoxaparin (Clexane)

1. Drug class
2. Indication
3. Dosage range, Frequency and best admin time
4. Monitoring
5. Counselling

Answer 1

1. Heparins (LMWH)
2. Prev of VTE in surgical pts, tx of VTE, prev of extracorporeal thrombosis during HD, Tx of STEMI, non-STEMI & unstable angina, tx of PE
3. SUBCUT
   Prev of VTE:
   Surgical patients mod risk: 20mg OD
   High risk or medical pts: 40mg OD
   for 7-10 days or until mobilised.

Tx of VTE:
1mg/kg BD OR 1.5mg/kg OD until adequate ORAL anticoagulation is achieved.
USE BD DOSE IF: Ca, recurrent VTE, smx PE, obesity.

STEMI- give w/aspirin

4. Monitoring
5. Counselling