Antiprotists Flashcards
1
Q
Chloroquine
A
Use = malaria
–> resistance? Use mefloquine
MoA = concentrates in parasite acidic food vacuole + prevents digestion of haem needed by parasite as source of essential AA
2
Q
Pyrimethamine
A
Use = malaria + Toxoplasma gondii MoA = dihydrofolate reductase inhibitor (folic acid synthesis)
3
Q
Metronidazole
A
Use = trichomoniasis, amoebiasis + giardiasis MoA = inhibits DNA gyrase + so nucleic acid synthesis
