Antiprotozoans Flashcards
1
Q
Toxopalsomsis Tx
A
pyrimethamine
2
Q
T. brucei Tx
A
suramin
melarsoprol
3
Q
T. cruzi Tx
A
nifurtimox
4
Q
leishmaniasis Tx
A
Na Stibogluconate
5
Q
Chloroquine MOA
A
blocks detoxification of heme into hemozoin –> accumulates and is toxic to plasmodia
6
Q
Why is chloroquine not used for P. falciparum
A
too high resistance
membrane pumps
7
Q
Tx in US for life threatening malaria
A
quinidine
artisunate
8
Q
Tx of life threatening malaria other than US
A
Quinine
9
Q
Chloroquine toxicity
A
retinopathy
10
Q
Chloroquine coverage
A
Plasmodial species other than flaciparum
11
Q
Rx’s that immobilize helminths
A
Mebendazole Pyrantel Pamoate Ivermectin Diethylcarbamazine Praziquantel
12
Q
Rx for trematodes (flukes)
Schistosoma
A
Praziquantel
