Antipsychotics Flashcards
What are the 2 groups of antipsychotics?
Typical
Atypical
What are antipsychotics used for?
Schizophrenia
Causes of : Psychosis, Mania, Agitation
Why do we give atypical antipsychotics instead of typical antipsychotics?
Atypical antipsychotics don’t have extra-pyramidal side-effects
2 examples of typical antipsychotics?
Haloperidol
Chlopromazine
3 examples of atypical antipsychotics?
Olanzapine
Risperidone
Clozapine (monitor)
4 extrapyramidal side-effects?
Parkinsonism
Acute dystonia
Akathisia (severe restlessness)
Tardive dyskinesia (sudden uncontrolled movements)
What 2 conditions are elderly recipients of antipsychotics at increased risk of?
Stroke
Venous thromboembolism
4 anti-muscarinic side-effects of typical anti-psychotics?
(moving down the body) Blurred vision Dry mouth Urinary retention Constipation
What are 3 common generic side-effects of anti-psychotics?
Sedation
Weight gain
Raised prolactin(!!) (may lead to galactorrhea)
What are 4 more niche anti-psychotic side-effects?
Impaired glucose tolerance
Neuroleptic malignant syndrome (pyrexia, muscle stiffness)
Reduced seizure threshold (greater with atypicals)
Prolonged QT interval (esp haloperidol)
What can you use to treat tardive dyskinesia?
Tetrabenazine (also used in Huntington’s to help with the involuntary movements)
What can you use to treat restlessness?
Propranolol
What can you use to treat acute dystonia?
Procyclidine
Benztropine
What can you use to treat a psychotic episode?
Lorazepam
