Antitussives Flashcards
Benzonatate brand name
Tessalon
Benzonatate indication/dosage
symptomatic relief of cough: 100mg TID PRN
Not indicated for children
Benzonatate max dosage
600mg/day
Benzonatate mechanism
peripheral anesthetizes stretch receptors in respiratory passages, lungs, and pleura by dampening activity, thus reducing cough reflex
Benzonatate drug interactions
None known
Benzonatate CI/precautions
Caution: allergy to anesthetic agents in para-aminobenzoic acid class (procain, tetracaine)
Severe life-threatening reactions, such as CV collapse and bronchospasm, have occured from chewing or sucking capsule
overdose may result in death
Benzonatate pregnancy category
C
Benzonatate ADR’s
drowsiness, headache, constipation, nausea, pruritis, nasal congestion, sensation of burning in eyes
Benzonatate patient education
SWALLOW CAPSULES WHOLE!!! do not chew or disolve, may be life-threatening
do not exceed prescribed dosage, may cause death
contact physician if you have difficulty swallowing or breathing shortly after dose
Chlorpheniramine + hydrocodone brand name
Tussionex
Chlorpheniramine + hydrocodone indication/dosage
relief of cough and upper resp symptoms associated with allergy or cold
1/2 (kids) to 1 (adults) tsp q12h
Chlorpheniramine + hydrocodone mechanism
Hydrocodone: narcotic, depresses cough reflex center in medulla oblongota
Chlorpheniramine: H1 histamine antagonist with anticholinergic activity
Chlorpheniramine + hydrocodone drug interactions
MAO-Is, TCAs, and CNS depressants
Chlorpheniramine + hydrocodone CI/precautions
CI: hypersensitivity
Caution: postoperative patients, patients with pulmonary disease, obstructive bowel disease, increased ICP, or head injury, patients with renal/hepatic impairment, narrow-angle glaucoma, asthma, prostatic hypertrophy, Addison’s disease
Chlorpheniramine + hydrocodone pregnancy category
C
