Upper Respiratory Agents

Question 1

Azelastine brand names

Answer 1

Astelin, Astepro

Question 2

Azelastine indication/dosage

Answer 2

treat symptoms of nonallergic rhinitis and seasonal allergic rhinitis in adults and children >12y: 2 sprays in each nostril BID
Priming required on first use and if lapse between doses >3 days

Question 3

Azelastine mechanism

Answer 3

H1-blocker, blocks histamine release in peripheral tissues

Question 4

Azelastine drug interactions

Answer 4

other CNS depressants may increase drowsiness

cimetidine may increase effects

Question 5

Azelastine CI/precautions

Answer 5

CI: hypersensitivity

caution when performing tasks requiring alertness

Question 6

Azelastine pregnancy category

Answer 6

C

Question 7

Azelastine ADR’s

Answer 7

bitter taste in mouth, headache, drowsiness, nasal burning, pharyngitis, dry mouth, sneezing, nausea, rhinitis, fatigue, dizziness, nosebleed, weight increase

Question 8

Azelastine patient education

Answer 8

may cause drowsiness, operate accordingly
prime with first use and if >3 day lapse between doses
store with pump unit tightly closed