Anxiolytics

Question 1

Alprazolam

Answer 1

Xanax

Question 2

Clonazepam

Answer 2

Klonipin

Question 3

Diazepam

Answer 3

Valium

Question 4

Lorazepam

Answer 4

Ativan

Question 5

What is the mechanism of action for benzos?

Answer 5

Enhance GABA neurotransmission

GABA is a inhibitory neurotransmitters

Question 6

what are the two short acting benzos?

Answer 6

Alprazolam

Lorazepam

Question 7

What is the most common Benzo?

Answer 7

Lorazepam - Ativan

Question 8

What is the drug of choice for status epilepticus?

Answer 8

benzos

Question 9

What are the 5 side effects of benzos?

Answer 9

CNS depression
Dependence
tolerance
Addictive 
Withdrawl potential

Question 10

What benzos have small amounts of renal clearance?

Answer 10

LOTS

lorazepam
oxazepam
tempazapam

Question 11

What is the BBW for benzos?

Answer 11

concomitant use of benzos and opioids may result in sedation, coma and death

Question 12

What schedule is benzos, and how many refills do they get per year

Answer 12

Schedule IV

5 refills/6mo

Question 13

Buspirone

Pro?
Con?

Answer 13

Pro- not much dependence potential

Con- takes a long time to work and has a short half life

Question 14

What is a non-addictive alternative drug for benzos?

Answer 14

buspirone

Question 15

pregabalin

Answer 15

lyrica

Question 16

gabapentin

Answer 16

neurontin

Question 17

What is the MOA for pregabalin and gabapentin

Answer 17

NOT SYNTHETIC GABA

inhibits glutamate release

Question 18

What class is pregabalin and what class is gabapentin and which med has to be reported to OARRS?

Answer 18

pregabalin - V

Gabapentin - VI and report to oarrs

Question 19

What is the major s/e of pregabalin and gabapentin?

Answer 19

renal insufficiency - need to adjust dose

Question 20

what drug do you adjust the dose for renal insufficiency?

Answer 20

pregabalin and gabapentin

Question 21

What 2 drugs are FDA approved for GAD?

Answer 21

venlafaxine - effexor

cymbalta

Question 22

What drug is approved for social anxiety disorder?

Answer 22

vanlafaxin

Question 23

What antihistamine is also used for anti-anxiety medication?

Answer 23

hydroxyzine

Question 24

What are the antidepressants you should use to treat anxiety?

Answer 24

antidepressants: SSRI, SNRI - venlofaxine and duloxetine or imipramine which is a TCA

Question 25

When you need to avoid benzos in someone who uses substances inappropriately what drug would you chose in treating anxiety?

Answer 25

buspirone

Question 26

Buspirone, BB's, antihistamines, SGAs, bupropion and trazadone are found to not be effective in which anxiety disorder?

Answer 26

panic disorder, you should use SSRI(Paxil/prozac), short acting benzos and psychotherapy

Question 27

What is the first line of treatment for OCD patients?

Answer 27

SSRIS!! Luvox

Question 28

What is a drug used to augment SSRIs in PTSD patients?

Answer 28

prazosin

Question 29

prazosin is indicated for what specific symptom?

Answer 29

prazosin is great for night terrors in people who have PTSD

Question 30

What is the most effective way to treat SAD?

Answer 30

psychotherapy

Question 31

Fluvoxamine is only approved by the FDA to treat?

Answer 31

OCD