Schizophrenia

Question 1

What is a loss of contact with reality?

Answer 1

psychosis

Question 2

What are positive symptoms associated with psychosis?

Answer 2

delusions
halucinations
disorganized speech/behavior

Question 3

what are negative symptoms associated with psychosis?

Answer 3

Abnormal affect
Avolation(no motivation)
Alogia(decreased output of speech)
Anhedonia(no interest in anything)
Asociality(no interest in people)

Question 4

What are fixed false beliefs?

Answer 4

delusions

Question 5

what type of belief is one that they will be harmed or harassed?

Answer 5

persecutory

Question 6

what is a belief that certain gestures, comments or environmental cues are directed at oneself?

Answer 6

referential

Question 7

What type of belief is the belief that one has exceptional abilities, wealth or fame?

Answer 7

grandiose

Question 8

what type of belief is the belief that another person is in love with them?

Answer 8

Erotomatic

Question 9

What type of belief is the belief that a major catastrophe will occur?

Answer 9

nihilistic

Question 10

what is the preoccupation with health and organ function?

Answer 10

somatic

Question 11

What is the difference between hallucinations and delusions?

Answer 11

Hallucinations are perceptions without any external stimuli… auditory, visual, olfactory, gustatory, tactile

Question 12

What is the difference between hallucinations and illusions?

Answer 12

illusions have an external stimulus - me with the June bug

true hallucinations are VIVID and clear

Question 13

hypnagGOGIC

Answer 13

illusions while falling asleep

Question 14

hypnoPOMPIC

Answer 14

illusions while waking up

Question 15

According to the DSM-5 there has to be at least 1 of which 3 qualities in a patient to diagnose schizophrenia

Answer 15

Delusions
Hallucinations
Disorganzied Speech

Question 16

What is going on with the following neurotransmitters in schizophrenia?
Dopamine
Glutamate
GABA (theory)
ACH (theory)

Answer 16

Dopamine: excess
Glutamate: under active NMDA receptors
GABA: interneuron abnormalities
ACH: possibly and issue here and schizophrenia patients self treat this aspect by smoking cigarettes

Question 17

Are positive or negative symptoms more crucial in determining a worse prognosis ?

Answer 17

negative symptoms

Question 18

What characterizes negative schizophrenia?

Answer 18

mostly negative symptoms
20% of cases
mostly males with family history

Question 19

How is schizophrenia differentiated from a mood disorder?

Answer 19

failure to return to baseline functioning after when in remission

Question 20

What are clang associations?

Answer 20

rhyming words

Question 21

what is echolalia?

Answer 21

repeating phrases

Question 22

orientation is generally ____________ in schizophrenia according to the PA ladies powerpoint?

Answer 22

unaffected

Question 23

What drug class is typically given for positive and negative schizophrenia symptoms?

Answer 23

SGA

Question 24

What 3 drugs can be given for agitation in schizophrenia patients? SHORT ACING IM

Answer 24

Haldol + lorazepam(Ativan) + benztropine(anticholinergic to prevent EPS)/ziprasidone/olanzipine

Question 25

What is the goal of treatment in schizophrenia patients?

Answer 25

prevent psychotic relapses and improve level of function and prevent brain cell death

Question 26

What class of antipsychotic medications helps with positive symptoms/DOPAMINE ANTAGONISt and what are the side effects?

Answer 26

first generation anti psychotics (haldol, perphenazine, chlorpromazine/thorazine) help with positive symptoms and the side effects include EPS symptoms

Question 27

What type of anti-psychotic meds that are serotonin-dopamine antagonists that may have better results for negative symptoms?

Answer 27

``` SGA-atypicals less EPS clozapine/clozaril risperidone/risperdal olanzapine/zyprexa ```

Question 28

What antipsychotic has shown to decrease positive schizophrenia symptoms?

Answer 28

clozapine

Question 29

What are the go-to anti-psychotic for schizophrenia?

Answer 29

abilify, risperdal, geodon, olanzapine

Question 30

When switching from an oral antipsychotic medication to a LAI you must continue oral medications for a while except for with which drug?

Answer 30

invega sustenna

Question 31

How do you treat dystonia?

Answer 31

benadryl

Question 32

How do you treat akathesia?

Answer 32

propranolol

Question 33

What medication can cause oculogyric crisis where the patients eyes roll back in their head?

Answer 33

haldol

Question 34

what EPS disorder does clozapine/clozaril not cause?

Answer 34

tardive dyskinesia

Question 35

LEAD PIPE RIGIDITY? | What drugs most commonly cause this?

Answer 35

neuroleptic malignant syndrome haldol and proloxin and antipsychotics will happen in first 2 wks of taken drug TREAT WITH CHLOROHEPTADINE

Question 36

What schizophrenic like disorder last 1-6mos?

Answer 36

schizophreniform

Question 37

What differentiates schizotypal and schizophrenia?

Answer 37

schizotypal is pervasive and does not go away... they are always weird

Question 38

What schizophrenia like disorder has history of a major mood disorder and then has delusions and hallucinations IN THE ABSENCE of a major mood disorder?

Answer 38

schizoaffective disorder - very tricky to diagnose

Question 39

What is the only FDA approved drug to treat schizoaffective disorder?

Answer 39

paliperidone Invega PO invega sustenna

Question 40

What differentiates delusional disorder from schizophrenia ?

Answer 40

criteria A for schizophrenia has never been met NO HALLUCINATIONS(that are unrelated to delusion) Functioning not impaired Behavior is not odd or bizarre not attributed to BPD, substance or medical condition

Question 41

What is the most common brief psychotic episode?

Answer 41

drug withdrawal