Apoptosis and necrosis Flashcards
1
Q
Apoptosis
A
Programmed cell death
2
Q
What happens to the cell during apoptosis?
A
Nucleus shrivels, whole cell shrivels, organelles packaged into vesicles and ‘eaten up’ by macrophages
3
Q
What is a common causes for cell apoptosis?
A
DNA damage (p53 monitors this)
4
Q
Caspases can also cause ___ and are turned on by fas receptors
A
apoptosis
5
Q
What can too much apoptosis cause?
A
Occurs in HIV. HIV binds to CD4 t-cells and inserts DNA, causing apoptosis
6
Q
What can a lack of apoptosis cause?
A
Tumours
7
Q
Necrosis
A
Traumatic cell death
8
Q
Clinical examples of necrosis
A
Cerebral infarction, frostbite, avascular necrosis of bone (scaphoid in wrist and neck of femur)
9
Q
A
