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TONO VASCULAR > ARAs (antagonistas del receptor de angiotensina AT1) > Flashcards

ARAs (antagonistas del receptor de angiotensina AT1) Flashcards

1
Q

Fármacos

A

Lorsatán, telmisartán, valsartán, candesartán

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2
Q

Mecanismo de acción

A

Antagonistas competitivos del receptor de angiotensina AT1

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3
Q

Características

A

No afecta bradicinina
Menos cardio-nefro protector
Efectos más lentos que los IECA
Efectos de 3 a 6 semanas

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4
Q

Indicaciones

A

Hipertensión arterial
Insuficiencia cardiaca
Nefropatía diabética
IAM

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5
Q

Reacciones adversas (lorsatán)

A

Dolor en piernas y espalda, calambres, acidez estomacal, menor sensibilidad al tacto

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6
Q

Reacciones adversas (telmisartán)

A

Somnolencia, mareos, aturdimiento, síncope

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7
Q

Reacciones adversas (valsartán)

A

Mareo, hipotensión, deterioro renal

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8
Q

Reacciones adversas (candesartán)

A

infección respiratoria, mareo, vértigo, cefalea, hipotensión, hiperkalemia, deterioro renal

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9
Q

Profármaco candesartán cilexetilo

A

Se hidroliza en tracto gastrointestinal en candesartán

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10
Q

FDA

A

C en el 1° trimestre, D en el 2° y 3°; evitar en lactancia

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TONO VASCULAR (5 decks)

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