Arrhythmias 1 and 2 Flashcards Preview

1st Year - Cardiology > Arrhythmias 1 and 2 > Flashcards

Flashcards in Arrhythmias 1 and 2 Deck (125):
1

What is an arrhythmia?

Abnormality of heart rate or rhythm

2

What are the 2 broad anatomical types of arrhythmias?

SupraventricularVentricular

3

What are the names of the 3 internal tracts that connect the SA node and AV node?

Anterior, middle and posterior internodal tracts

4

What are ectopic beats?Name when you have several of these in a row?

Beats or rhythms that originate in places other than the SA node (when the latent pacemaker fires at a rate faster than the SA node)Ectopic rhythm - ectopic focus dictates the entire rhythm

5

Are ectopic beats/ rhythms dangerous?

Depends how the affect the cardiac output

6

How can arrhythmias be categorised based on rate?

TachyarrhymiasBradyarrhytmias

7

What are the 4 types of atrial tachycardia? (SVT)

Atrial fibrillationAtrial flutterEctopic atrial tachycardiaSinus tachycardia

8

What are the 2 types of atrial bradycardia?

Sinus bradycardiaSinus pauses

9

What are the 3 types of atrioventricular node arrhythmias?

AV node re-entryAccessory pathwaysAV block

10

What are the 4 types of ventricular arrhythmias??

Premature ventricular complexVentricular tachycardiaVentricular fibrillationAsystole

11

What are the clinical causes of arrhythmias? (5)

Abnormal anatomy e.g. left ventricular hypertrophy, accessory pathwaysAutonomic e.g. sympathetic stimulation (nervousness, hyperthyroidism), increased vagal toneMetabolic e.g. hypoxic myocardium, ischaemic myocardium, electrolyte imbalancesInflammation e.g. viral myocarditis]DrugsGenetics (mutations of cardiac ion channels) e.g. congenital long QT syndrome

12

What are the 5 mechanisms of arrhythmias?

Defects in impulse formation (altered automaticity, triggered activity)Defects in impulse conduction (re-entry, accessory tracts, conduction block)

13

What is altered automaticity?

When a latent pacemaker takes over the SA nodes function as the normal pacemaker of the heart (causes escape or ectopic beats) - can occur physiologically when the ANS modulates the SA nods activity e.g. caused by drugs, ischaemia

14

What is triggered activity?

When abnormal action potentials are triggered by a preceding action potential resulting in the heart cells beating twice e.g. tornadoes de points

15

What is re-entry?

Self-sustaining electrical circuit stimulates an area of the myocardium to be stimulated repeatedly

16

What is conduction block?

Any disease that disrupts electrical conduction may reduce conduction or cause heart block

17

What are accessory pathways?

Additional electrical conduction pathway between 2 areas of the heart e.g. WPW

18

What effect does hypothermia have on phase 4 of AP slope?

Decreases it (altered automaticity)

19

What effect does hyperthermia have on phase 4 of action potential slope?

Increases it (altered automaticity)

20

What effect do hypoxia and hypercapnia have on phase 4 of AP slope?

increase it (altered automaticity)

21

What effect does hypokalaemia have on phase 4 of AP slope?

Increases it (also prolongs repolarisation and increases ectopics)

22

Symptoms of arrhythmias?

Palpitations (a noticeably rapid, strong or irregular heart beat)SOBDizinessSyncopeSudden cardiac deathWorsen pre-exisiting conditiosn e.g. angina

23

Investigations of arrhythmias? (&)

12 lead ECGCXREchocardiogramStress ECG24 hours ECG hotter monitoringEvent recorderElectrophysiological (EP) study

24

Why is an ECG done for arrhythmias?

To assess rhythmSigns of previous MI, pre-excitation (WPW)

25

What sign on an ECG suggests a previous MI?

Pathological Q waves

26

Why perform an exercise ECG in a patient with suspected arrhythmia?

To assess for ischaemiaExercise induced arrhythmia

27

Why perform a 24 hour hotter ECG in a patient with suspected arrhythmia?

To assess for paroxysmal arrhythmiaTo link symptoms to underlying heart rhythm

28

Why perform an echo in a patient with suspected arrhythmia?

To assess for structural heart disease

29

Why perform an electrophysiological study in a patient with a suspected arrhythmia?

To trigger the arrhythmia and study its mechanismOpportunity to treat by ablation at the same time

30

What are the symptoms of atrial ectopic beats?

Asymptomaticpalpitations

31

Treatment of atrial ectopic beats?

Generally no treatment but patients may find B blockers helps (avoid stimulants e.g. caffeine)

32

When is sinus bradycardia physiological?

Athlete

33

What is sick sinus syndrome?

Sinus node dysfunction causing bradycardia +/- rest, senatorial block, or SVT alternating with bradycardia/ asystole

34

What are causes of sinus bradycardia?

Drugs e.g. beta blockersIschaemiaLots more

35

Treatment of sinus bradycardia?

Atropine (if acute, e.g. MI)Pacing if haemodynamic compromise e.g. hypotension, CHF, angina, collapse

36

Causes of sinus tachycardia?

Physiological in anxiety, fever, hypotension, anaemiaInappropriate due to drugs, etc.

37

Treatment of sinus tachycardia?

Treat underlying causeB-adrenergic blockers

38

What is an example of a paediatric vagal manoeuvre (used to treat SVT)?

ice water to face for infantsBlow through straw (valsalva) for child or adolescents

39

What is the most common cause of SVT?

Atriventricular re-entry

40

What causes atrioventricular re-entry anatomically?

A small re-entry circuit involving the atrioventricular node and surrounding atrial tissue

41

What is wolf-parkinson-white?

Presence of an accessory pathway between the atria na ventricles causing ventricular pre-excitation

42

What type of abnormality does WPW cause on an ECG?

Delta waves

43

Acute management of SVT?

Vagal manoeuvresIV adenosine (extremely short half life so have to push it in as fast as you can)IV verapamil

44

Chronic management of SVT?

Avoid stimulantsRadifrequency ablationAnti-arrhythmic drugs (Class II or IV)

45

What is cardiac ablation?

Selective cauterisation of cardiac tissue to prevent tachycardia, targeting either an automatic focus or part of a re-entry circuit

46

What does cardiac ablation involve?

Placement of catheters in heart via femoral veinsIntracardiac ECG recorded during sinus rhythm, tachycardia and during pain manoeuvresCatheter placed over focus/ pathway and tip heated

47

What causes AV node conduction disease?

Ageing processAcute MIMyocarditisInfiltrative disease e.g. amyloidDrugs e.g. B blcokers, Calcium channel blockersCalcific aortic valve diseasePost-aortic valve diseasesGenetic e.g. Lenore's disease, myotonic dystroph

48

1st degree heart block?

PR interval prolonged (greater than 0.2 seconds)

49

Treatment of 1st degree heart block?

None - long term follow up recommended as more advanced block may develop

50

What are the 2 types of 2nd degree heart block?

Mobitz IMobitz II

51

What is Mobitz I?

Prolong PR interval cumulating in a droped ventricular beat (QRS complex)

52

what is Mobitz II?

Regularly more than one P wave to each QRS complex in a 2:1, 3:1 or 4:1 ratio

53

Treatment of mobitz II?

Permanent pacemaker

54

Treatment of mobitz I?

Ventricular pacing

55

What is third degree heart block?

Complete atrioventricular dissociation: regular P waves, regular QRS complexes but no association between the 2

56

Treatment of 3rd degree heart block?

Ventricular pacing

57

What is trancutaneous pacing?

Using a defibrillator to pace the heart during an emergency (other type is transvenous)

58

What are the 2 types of pacemakers available?

Single chamber (paces the right atria or right ventricle only)Dual chamber (paces the RA and RV)

59

What is a single chamber pacemaker used for?

Atrial = isolated SA node disease but normal AV nodeVentricular = AF with slow ventricular rate

60

What is a dual chamber pacemaker used for?

Maintains AV synchrony - AVN disease

61

What are premature ventricular complexes?

ectopic impulses originating from an area distal to the His Purkinje system. VPCs are the most common ventricular arrhythmia

62

What causes premature ventricular complexes?

May not have structural heart diseaseIschaemic heart diseaseHypertension with left ventricular hypertrophyHeart failureMay be marker for inherited arrhythmia syndrome

63

Symptoms of premature ventricular complexes?

Usually asymptomatic

64

Treatment of premature ventricular ectopics?

Beta blockers

65

What is a broad complex tachycardia in a patient with no history of cardiac disease?

VT

66

What is ventricular tachycardia?

Tachycardia originating from a ventricular focus

67

Is VT life threatening?

Yes

68

What type of patients does VT occur in?

Usually those with significant heart disease e.g. coronary artery disease Rarely, cardiomyopathyInherited syndrome e.g. long QT, Brugada syndrome(look for cause of VT .e.g electrolytes (hypokalaemia, hypomagnesaemia, ischaemia, hypoxia, medications)

69

what is long QT syndrome?

a rare inherited or acquired heart condition in which delayed repolarization of the heart following a heartbeat increases the risk of episodes of torsades de pointes

70

What is Brugada syndrome?

a genetic disease that is characterised by abnormal electrocardiogram (ECG) findings and an increased risk of sudden cardiac death.

71

Difference between monomorphic and polymorphic VT?

in mono. QRS = symetricalIn poly. QRS = unsymetrical

72

What is ventricular fibrillation?

Chaotic ventricular electrical activity which causes the heart to lose the ability to function as a pump

73

Treatment of VF?

Defibrillation and cardiopulmonary resuscitation

74

Treatment of VT?

DC cardioversion if unstableIf stable consider pharmacologic cardioversion with AADIf unsure if VT or something else, consider adenosine to make a diagnosis

75

what long term treatments are available for VT?

Implantable cardiovertor defibralltorsCHF therapies

76

What is normally the cause of ventricular arrhythmias?

Structural problems

77

What causes atrial flutter?

rapid heart rate causes by re-entry circuits in the atrium

78

Appearance of atrial flutter on ECG?

Saw tooth appearance

79

What is atrial fibrillation caused by physiologically?

Rapid, unsynchronised and chaotic electrical activity which causes conduction of irregular signals to the ventricles due to multiple weavlets of re-entry and ectopic focus around the pulmonary veins

80

What results in increased R wave amplitude in the left-sided ECG leads (I, aVL and V4-6) and increased S wave depth in the right-sided leads (III, aVR, V1-3)?

Left ventricular hypertrophy

81

Type of heart beat in A Fib?

Irregular

82

What are the 3 different types of AFib?

ParoxysmalPersistentPermanent (chronic)

83

What is paroxysmal AFib?

Reverts to sinus rhythm spontaneously - often recurrent

84

What is persistent AFib?

AF that is not self terminating/ has lasted longer than 7 days but can be terminated through treatment

85

What is permanent AFib?

Continuos AF that cannot be successfully terminated

86

What does incidence of AFib increase with?

Age

87

Associated diseases/ causes of AFib?

HypertensionCongestive heart failureSick sinus syndrome - "tachy brady syndrome"Coronary heart diseaseThyroid diseaseFamilialValvular heart diseaseAlcohol abuseCongenital heart diseaseCardiac surgeryOther rarer causes e.g. COPDEither classified into cardiac or non-cardiac cause

88

What is lone (idiopathic) AFib?

Absence of any underlying cause for AF (diagnosis of exclusion)

89

Symptoms of AFib?

PalpitationsPre-syncope (dizziness)SyncopeChest painDyspnoeaSweatinessFatigueCan be asymptomaticSymptoms often worse at the onset of AF

90

Termination of atrial fib?

pharmacological cardioversion with anti-arrhythmic drugs (30% effective)Electrical cardioversion (90% effective)Spontaneous reversion to sinus rhythm

91

What are the anti-arrhythmic drug examples that can be used to terminate and prevent atrial fib?

FlecainideSotalolAmiodarone

92

ECG of atrial fib?

Atrial rate greater than 300 bpm

93

Rhythm in Atrial Fib?

Irregularly irregular

94

Ventricular rate in atrial fib?

Variable (dependent upon AV node conduction properties, sympathetic and parasympathetic tone, presence of drugs which act on the AV node)

95

Recognition of atrial fib on ECG?

Absence of P waves, presence of f waves - ventricular rate is irregular

96

What pharmacological agents are useful in controlling ventricular rate in AF by decreasing conduction in the AV node?

Beta blcokersCalcium channel blcokers

97

Ventricular rate in A fib?

IrregularCan be slow, normal or fast (and ranging between these) - depends on AV node conduction properties, sympathetic and parasympathetic tone, presence of drugs which act on the aV node (e.g. flecanide, sotolol, amiodarone)

98

What is it called when AF goes so fast that it looks regular but it actually its?

Pseudoregularisation

99

How does AF cause a reduced cardiac output?

Lost atrial kick and decreased killing time

100

If the patient has hypertrophic cardiomyopathy, what can AFib result in?

Congestive heart failure

101

What does ventricular rates less than 60bpm in AF suggest?

AV conduction disease

102

Management of AF?

Rhythm control (maintain SR predominantly)ORRate control: Accept AF but control ventricular rateAnti-coagulation for both approaches if high risk for thromboembolism

103

Rate control during AFib?

Pharmacological therapy to slow down AVN conduction:DigoxinBetablcokersVerapamil, diltizamGive the above alone or in combinationIf the above doesnt work, the aV node can be completely ablated and a pacemaker fitted

104

Rhythm control of Afib?

Restoration of NSR:Pharmacological cardioversion (anti-arrhythmic drugs e.g. amiodarone)Direct current cardioversionMaintenance of NSR:Anti-Arrhythmic drugsCatheter ablation of atrial focus/ pulmonary veinsSurgery (Maze procedure)

105

Treatment of paroxysmal AF?

Rhythm control:Cardiovert (pharma/ DC)Anti-Arrhythmic drugs to preventAnti-coag

106

Treatment of persistent or permanent AF?

Rate control (digoxin, beta blocker, verapamil or diltiazem)Anti-coagulation if high riskDC cardioversion if structurally normal heart

107

what is tornadoes de pointes?

a specific form of polymorphic VT in patients with a long QT interval. It is characterized by rapid, irregular QRS complexes, which appear to be twisting around the ECG baseline - it can be acquired or congenital (very deadly form of vt)

108

Heart rate in torsades de points?

200-250 bpm

109

Rhythm in torsades de pointes?

Irregular (In comparison to normal VT)

110

Recognition of tornadoes de pointes?

Long QT intervalWide QRSContinuously changing QRS morphology

111

Events leading to Torsdaes de points?

hypokalaemiaProlongation of AP duration (drug induced)Renal impairment (increased drug levels)

112

What is the scoring system used to assess risk of thromboembolism in atrial fib?

CHADVASC score

113

What is the CHADSVASC score

 C   Congestive heart failure (or Left ventricular systolic dysfunction) 1  H  Hypertension: blood pressure consistently above 140/90 mmHg (or treated hypertension on medication) 1  A2  Age ≥75 years 2  D  Diabetes Mellitus 1  S2  Prior Stroke or TIA or thromboembolism 2  V  Vascular disease (e.g. peripheral artery disease, myocardial infarction, aortic plaque) 1  A  Age 65–74 years 1  Sc  Sex category (i.e. female sex) 1 Score is 1 maybe antii-cogaulantIf 2 or greater then you should be on anti-coagulants

114

What puts patients at a high risk of thromboembolism?

Valvular heart diseaseAge greater than 75 especially femaleHypertensionHeart failurePrevious TE/strokeCoronary artery disease or diabetes and greater than 60yoThyrotoxicosis

115

Indications for anti-coag in AF?

Valvular AF (mitral valve disease)Non valvular AF if:Age greater than 75HypertensionHeart failurePrevious stroke/ thromboembolismCAD/ DMDaibetes

116

Bleeding risk assessment for AF?

HAS BLEDHypertension 1Abnormal renal or liver function 1 or 2Stroke 1Bleeding 1Labile INRs 1Elderly (age greater than 65) 1Drugs or alcohol 1 or 2(if score is greater than 3 = high risk)

117

Why type of ablation is done in AF to maintain sinus rhythm?

Ablating AF focus

118

What type of ablation is done in AF to control rate?

Ablation of AVN to stop fast conduction to the ventricles

119

Is Atrial flutter regular or irregular?

Regular - usually paroxysmal and is rapid

120

Where is the re-entry circuit in atrial flutter?

Right atrium

121

How long can episodes of Atrial flutter last?

Seconds to years

122

What does chronic atrial flutter usually progress to?

Atrial fibrillation

123

Risk of atrial flutter?

May result in thrombi-embolism

124

Characteristic feature of Atrial flutter on eCG?

Regular rapid rate with saw root F wave

125

Treatment of Atrial flutter?

RF ablationPharmacological therapy to slow the ventricular rate = restores sinus rhythm, and maintains sinus rhythm once convertedCardioversionWarfarin for prevention of thromboembolism