Flashcards in Assessment of Hematologic System Deck (123)
What is hematology?
The study of blood and blood forming tissues. Includes the bone marrow, blood, spleen, and lymph system
A basic knowledge of hematology is useful in clinical settings to evaluate the patients ability to transport 02 and CO2, maintain ____________ volume, coagulate blood and combat ____________
intravascular volume; infections
The assessment of the hematologic system is based on ......
diagnostic studies, physical examination and the patients health history
What is hematopoiesis ?
Blood cell production that occurs within the bone marrow
Which type of marrow actively produces blood cells ?
Red bone marrow
Where is the red marrow primarily found ?
In the flat and irregular bones such as the ends of long bones, vertebrae, sacrum, sternum, ribs, flat cranial bones and scapulae
What are the three types of blood cells ?
WBC, RBC, platelets
When tissue hypoxia occurs, what happens , regarding the production of blood cells ?
Erythropoietin, a cytokine protein, is released by the liver and kidney and it circulates to the bone marrow and stimulates the production of RBC.
Albumin helps to regulate the ________ ____________ within the blood
another name for platelets
Blood is a type of ___________ tissue that performs 3 major functions: ______, ______ , ______.
connective; regulation; protection; transportation
primary function of erythrocytes
transport O2 and CO2 and maintain acid base balance
Hemoglobin that has oxygen bound to it is referred to as
hemoglobin is composed of what two compounds?
Heme (an iron compound) and globin (a simple protein)
The heme portion of hemoglobin binds to ......
The globin portion of hemoglobin binds to
the process of RBC production
What is erythropoiesis regulated by ?
cellular O2 requirements and general metabolic activity
Erythropoiesis is stimulated by _________ and controlled by _________________
What glycoprotein growth factor stimulates the red bone marrow to produce RBC ?
About how many RBC are produced per second during erythropoiesis?
Erythropoiesis is influenced by the availability of certain ______________ and _______________
nutrients and hormones
What is a reticulocyte?
Immature red blood cell
A reticulocyte can develop into mature RBCs within how many hours upon release into the circulation ?
Assessing the number of reticulocytes is a useful means of evaluating .......
the rate and adequacy of erythrocyte production
destruction of RBC by macrophages and monocytes `
Hemolysis normally occurs where?
In the bone marrow, spleen, and liver
bilirubin; how does it relate to hemolysis ?
one of the components of RBC; when hemolysis occurs, there is an increased amount of bilirubin to be processed by the body. When hemolysis occurs via normal mechanisms, the liver is able to conjugate and excrete all bilirubin that is released
Leukocytes have a widely available life span: granulocytes may only live for ________, yet some T lymphocytes may live for _______