Associations

Question 1

LDH

Answer 1

dysgerminoma

seminoma

Question 2

PTEN

Answer 2

endometrial carcinoma (endometrioid type)

Question 3

p53

Answer 3

endometrial carcinoma (serous type)

ovarian cancer (high grade serous)

Question 4

i(12p)

Answer 4

testicular cancer

Question 5

TMPRSS2/ERG fusion

Answer 5

prostate cancer

Question 6

LSIL vs HSIL

Answer 6

nuclear:cytoplasmic ratio

HSIL: nucleus takes up almost entire cell (higher ratio)

LSIL: more cytoplasm

neither form a mass

Question 7

fused glands

Answer 7

adenocarcinoma

Question 8

epithelial cell ovarian tumors are more common in ______

Answer 8

ADULTS (pre/peri/post menopausal)

serous
mucinous
endometrioid
clear cell
Brenner

Question 9

germ cell ovarian tumors are more common in ______

Answer 9

young adults (15-20 ish yrs)

dysgerminoma 
embryonal 
yolk sac
choriocarcinoma
teratoma

Question 10

sex cord stromal ovarian tumors are more common in ______

Answer 10

older adults (50’s)
granulosa
thecoma/fibroma

sertoli-leydig exception (24 yrs)

Question 11

solid ovarian tumors

Answer 11

dysgerminoma
choriocarcinoma
immature teratoma
thecoma/fibroma
sertoli/leydig

Question 12

call-exner body

Answer 12

granulosa tumor (ovarian)
ESTROGEN

Question 13

coffee bean nucleus

Answer 13

granulosa tumor (ovarian)

Question 14

HCG

Answer 14

choriocarcinoma

Question 15

AFP

Answer 15

yolk sac

Question 16

CA 125

Answer 16

serous adenocarcinoma

Question 17

serotonin

Answer 17

carcinoid

Question 18

thyroid hormone

Answer 18

struma ovarii

Question 19

estrogen

Answer 19

theca/granulosa

Question 20

androgen

Answer 20

leydig

Question 21

causes of endometrial CA

Answer 21

granulosa/thecoma (unopposed estrogen)

endometrioid CA of ovary

Question 22

fallopian tube STIC

Answer 22

serous carcinoma of ovary

Question 23

psammoma bodies

Answer 23

serous carcinoma of ovary (any papillary tumor)

Question 24

AFP

Answer 24

yolk sac

Question 25

acetylcholinesterase

Answer 25

neural tube defect

Question 26

proliferative breast lesions with an increased risk of carcinoma:

Answer 26

adenosis | intraductal papilloma

Question 27

papilloma lined by epithelium stromal core

Answer 27

intraductal papilloma

Question 28

- epithelial lining w no atypia - fibrous stroma - slit like space - well demarcated

Answer 28

fibroadenoma

Question 29

hyperplastic nodules of stroma/glands lined by 2 layers of epithelium

Answer 29

BPH

Question 30

glands lined by a single layer of epithelium and packed back to back

Answer 30

adenocarcinoma

Question 31

foci of chronic inflammatory cells in the stroma and normal appearing glands

Answer 31

prostatitis

Question 32

areas of necrosis filled w neutrophils

Answer 32

abscess