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Asthma Flashcards

1
Q

What rescue inhaler use Characterizes intermittent asthma severity?

A

<=2 days per week

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2
Q

What rescue inhaler use shows persistent mild severity?

A

> 2 days per week but not daily or >1x/day

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3
Q

What rescue inhaler use shows persistent moderate asthma severity?

A

Daily

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4
Q

What rescue inhaler use shows persistent severe severity?

A

Several times per day

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5
Q

What vaccines should asthma patients get?

A

Annual flu

Pneumovax 23

Patients should only get Prevnar if they are 6-18 who require high dose oral steroids

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6
Q

What drug is first line for all patients with persistent asthma?

A

ICS

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7
Q

What agent should never be used alone in asthma and is a preferred add on?

A

LABA

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8
Q

What drug is used for severe allergic asthma?

A

Mab: Omalizumab

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9
Q

When should you maintain current asthma therapy or consider step down?

A

Consider step down if controlled for at least 3 months

  • Symptom use: of SABA <= 2 days per wk, nightime <=2 days per wk , no limitations on activity
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10
Q

When should you consider stepping therapy up for asthma patients?

A

SABA > 2 days per wk

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11
Q

When should you consider stepping asthma therapy up 1-2 steps?

A

Using SABA several times a day

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12
Q

What is the recommended therapy for intermittent asthma? 2 things

A

SABA as needed

COnsider low dose ICS to prevent exacerbations

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13
Q

Step 2 what should be added for mild persistent asthma

A

Low dose ICS, controller

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14
Q

What should be added for Step 3 moderate persistent asthma?

A

Low dose ICS + LABA OR medium dose ICS

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15
Q

What should be addd in step four for persistent severe asthma?

A

Medium dose ICS + LABA

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16
Q

What should be added in step 5 fpr severe persistent asthma?

A

High dose ICS + LABA

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17
Q

Step 6 severe persistent asthma?

A

Add oral steroid

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18
Q

What is added for Step 1,2,3,4,5,6

A
  1. SABA, consider low dose ICS
  2. Add ICS for sure low dose
  3. Low dose ICS + LABA or increase ICS
  4. Increase dose of ICS +LABA
  5. Hign dose ICS + LABA
  6. Add oral sterois
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19
Q

Albuterol dosing?

A

MDI/DPI 1-2 inhalations Q4-6

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20
Q

Boxed warning for ProAir Respiclick?

A

Severe hypersens milk protein

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21
Q

SEs of albuterol? 7

A
  1. Nervousness
  2. Tremor
  3. Tachcardia
  4. Palpitations
  5. COugh
  6. Hyperglycemia
  7. Decreased K
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22
Q

Serevent Diskus?

A

Salmeterol

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23
Q

Boxed warning for serevent diskus?

A

Increase asthma related deaths only used in combo with asthma

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24
Q

Qvar

A

Beclomethasone

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25
Pulmicort Flexhaler
Budesonide
26
Pulmicort Respules
Budesonide Nebulaizer
27
Flovent Arnuity Ellipta?
Fluticasone
28
SEs of Inhaled corticosteroids? 3
1. Dsyphania difficulty speaking 2. Oral candiasis 3. Cough
29
How to prevent oral candiasis in asthma?
Rinse mouth after use use a spacer
30
What is the only ICS available as a nebulizer?
Pulmicort respulesL Budesonide
31
What is a high dose of QVAR?
\>480 mcg
32
What is a high dose of pulmicort?
\>1080
33
What is a high dose fluticasone MDI?
\>440
34
What is a high dose of fluticasone DPI?
\>500
35
What is a high dose of mometasone MDI
\>400
36
What is a high dose of mometasone DPI?
\>440
37
Special note about QVAR and Alvesco?
They do not need to be shaken
38
Main ICSs for asthma? 3
QVAR, Pulmicort, Flovent
39
One LABA used for Asthma and COPD
Salmeterol Serevent
40
4 combo ICS LABA for Asthma
1. Symbicort 2. Advair, Airduo 3. Dulera 4. Breo Ellipta
41
Breo Ellipta?
Fluticasone/vilanterol
42
Dulera
Mometasone/formeterol
43
Advair, Airduo
Fluticasone/salmeterol
44
What are the DPI names? 7
1. Diskus 2. Ellipta 3. Pressair 4. Handihaler 5. Neohaler 6. Respiclick 7. Flexhaler
45
What dosage forms does singulair com ein?
Tablet, chewable, packet
46
3 dosing ranges for Singulair
1. \>14, 10 mg in the evening 2. 6-14, 5 mg in the evening 3. 1-5, 4 mg in the evenin
47
Singlulair warning?
Neuropsych events
48
Theophylline therapeutic levels
5-15 mcg/mL
49
How do you convert theophylline to aminophylline
ATM amino to theo x 0.8 theo to amino / 0.8
50
What 7 drugs can increase theophylline levels
1. CYP1A2 inhibiton 2. Ciprofloxacin 3. fluvoxamine 4. cimetidine 5. propranolol 6. zafirlukast 7. zilueton
51
Xolair
Omalizumab
52
Xolair administration?
In a medical setting given SC Anaphylaxis can occur
53
What does Xolair do?
IgE binding inhibitoon only for allergic asthma
54
Who is at higher risk for developing COPD?
alpha-1 antitrypsin def
55
Difference in asthma and COPD?
Asthma the limitation in airflow is medically reversible COPD: Not fully reversible
56
What is required for COPB diagnosis?
Spirometry
57
What FVC confirms COPD?
FVC\<70
58
Pts exacerbation history and CAT/mMRC score to put them in category A
0 or 1 exacerbation not leading to hosptalization CAT \<10 mMRC 0-1
59
Exacerbation hx to put you in COPD category A or B
0 or 1 not leading to hospitalization
60
CAT and mMRC score putting you in category D or B
CAT\>= 10 mMRC \>= 2 `
61
Exacerbation history to put you in category C or D
\>= 2 exacerbations or 1 putting you in the hospital
62
Recommended treatment for category A
SABA or SAMA PRN
63
Category B treatment
LAMA or LABA
64
Pt group C
LAMA
65
Patient Group D
LAMA + LABA
66
Atrovent HFA
Ipratropium
67
Combivent REspimat
Ipratropium + albuterol
68
Spiriva Handihaler
Tiotropium
69
Brovana
Arformeterol R-Isomer of formeterol
70
Daliresp
Roflumilast
71
MOA of daliresp
PDE-4 inibitor incres cAMP redcing inflammation in the lungs

NAPLEX (64 decks)

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