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Therapeutics > Asthma/ COPD Medications and Staging > Flashcards

Asthma/ COPD Medications and Staging Flashcards

(162 cards)

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1
Q

Beclomethasone Brand Name

A

QVAR

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2
Q

Beclomethasone dosage form

A

Redihaler (MDI)

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3
Q

Beclomethasone class

A

Inhaled corticosteroids (ICS)

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4
Q

Beclomethasone age groups

A

5-11; adults

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5
Q

Budesonide brand

A

Pulmicort

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6
Q

Budesonide dosage form

A

Flexhaler (DPI) and Respules (nebulizer solution)

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7
Q

Budesonide class

A

ICS

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8
Q

Budesonide age groups

A

Flexhaler: 5-11; adults
Nebulizer: 0-4, 5-11

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9
Q

Budesonide counseling notes

A

Respules should be used with jet nebulizer and should not be mixed with other solutions

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10
Q

ciclesonide brand

A

Alvesco

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11
Q

ciclesonide dosage form

A

HFA; MDI

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12
Q

ciclesonide class

A

ICS

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13
Q

ciclesonide age groups

A

6-adult

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14
Q

Fluticasone propionate brand

A

Flovent, ArmonAir

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15
Q

fluticasone propionate dosage form

A

HFA (MDI), DPI, Aerosol Powder Inhaler (Digihaler)

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16
Q

fluticasone propionate age groups

A

Flovent- 4-adult
Armon Air Digihaler- adults only

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17
Q

fluticasone propionate class

A

ICS

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18
Q

fluticasone furoate brand

A

arnuity ellipta

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19
Q

fluticasone furoate dosage form

A

ellipta (DPI)

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20
Q

fluticasone furoate age groups

A

5-11; adult

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21
Q

mometasone brand name

A

Asmanex

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22
Q

mometasone dosage form

A

HFA (MDI), Twisthaler (DPI)

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23
Q

mometasone age groups

A

4-11; adults

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24
Q

what disease states can ICS be used for

A

asthma, copd

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25
do intermittent asthma patients need ics?
no
26
ICS adverse effects
oral thrush, cough, dysphonia (difficulty speaking)
27
ICS counseling tips
patients should rinse mouth to prevent thrush, most effective long-term control therapy for asthma, may increase pneumonia risk in COPD patients (immune suppression), use lowest effective dose (high dose increases risk for systemic side effects).
28
LABA MOA
increase cAMP, relaxes bronchial smooth muscle and inhibit hypersensitivity mediators from mast cells (histamine and leukotrienes)
29
ICS MOA
immune suppression; prevent and control inflammation
30
Arformoterol tartrate brand
Brovana
31
arformoterol tartrate dosage form
nebulizer solution
32
arformoterol tartrate age groups/indication
adult; copd only
33
formoterol brand name
Perforomist
34
formoterol dosage form
nebulizer solution
35
formoterol age groups/ indication
adult only; COPD only unless used with ICS
36
indacaterol brand name
arcapta neohaler
37
indacaterol dosage form
neohaler (DPI)
38
indacaterol age group/indication
adult; COPD only
39
olodaterol brand name
Striverdi respimat
40
olodaterol dosage form
respimat (soft mist inhaler)
41
olodaterol age group/ indication
adult; COPD only
42
Salmeterol brand name
Serevent Diskus
43
salmeterol dosage form
Diskus (DPI)
44
salmeterol age groups/ indication
4-11, adult, COPD, asthma when used with ICS
45
LABA adverse effects
tachycardia, headache, tremor, hypokalemia (low potassium)
46
LABA boxed warnings
risk of asthma related death when used as a monotherapy; risk of increased hospitalizations in pediatric and adolescent patients
47
Can children under 4yo used a DPI
no; not enough inspiratory flow
48
LABA counseling points
prolonged QT seen with intentional overdoses, not for acute symptoms, helpful for exercise-induced bronchospasm, formoterol and indaceterol capsules should not be taken orally.
49
What does LABA stand for?
Long Acting Beta Agonist
50
What does LAMA stand for?
Long Acting Antimuscarinics
51
What is the MOA for LAMAs?
block the bronchoconstrictor effects of acetylcholine on M3 and M2 receptors
52
Aclidinium brand name
Tudorza Pressair
53
Aclidinium dosage form
Pressair (DPI)
54
Aclidinium age/ indication
adult; COPD only
55
Glycopyrrolate brand name
Seebri Neohaler
56
Glycopyrrolate dosage form
DPI (breezhaler/neohaler); Nebulizer Solution
57
glycopyrrolate age/ indication
adult; COPD only
58
revefenacin brand name
Yupelri
59
revefenacin dosage form
nebulizer solution
60
revefenacin age group/ indication
adult; COPD only
61
Tiotropium brand name
Spiriva
62
tiotropium dosage form
Handihaler (DPI) Respimat (soft mist inhaler)
63
tiotropium age groups/ indications
Handihaler; adult; copd only respimat; 12-adult; asthma or COPD
64
umeclidinium brand name
incruse ellipta
65
umeclidinium dosage form
ellipta (DPI)
66
umeclidinium age/indication
COPD only
67
LAMA adverse effects
dry mouth, dizziness, blurred vision, upper respiratory infections, paradoxical bronchospasms
68
fluticasone/salmeterol brand
Advair; Airduo & Airduo digihaler
69
fluticasone/salmeterol dosage form
Diskus (DPI) HFA (MDI) Respiclick (Airduo only) (DPI)
70
fluticasone/salmeterol age groups/indication
diskus (DPI)- 4-adult; asthma or COPD HFA (MDI)- adult only; asthma or COPD
71
Budesonide/ Formoterol brand
Symbicort
72
budesonide/formoterol dosage form
HFA (MDI)
73
budesonide/ formoterol age group/ indication
5-11;adult; asthma or COPD
74
budesonide/formoterol class
ICS/LABA
75
mometasone/ formoterol brand
Dulera
76
mometasone/formoterol dosage form
MDI
77
mometasone/formoterol age group/indication
adult; asthma or COPD
78
mometasone/formoterol class
ICS/ LABA
79
fluticasone/vilanterol brand
Breo Ellipta
80
fluticasone/vilanterol dosage form
ellipta; DPI
81
fluticasone/vilanterol age/indication
adult; asthma or COPD
82
fluticasone/vilanterol class
ICS/LABA
83
olodaterol/tiotropium brand name
stiloto respimat
84
olodaterol/tiotropium dosage form
respimat (soft mist inhaler)
85
olodaterol/tiotropium age/indication
adult; copd only
86
olodaterol/tiptropium class
LABA/LAMA
87
vilanterol/ umeclidinium brand name
Anoro Ellipta
88
vilanterol/ umeclidinium dosage form
Ellipta/DPI
89
vilanterol/ umeclidinium age/indication
adult; COPD only
90
vilanterol/ umeclidinium class
LABA/LAMA
91
Incadaterol/glycopyrronium brand name
Utibron Neohaler
92
Incadaterol/glycopyrronium dosage form
neohaler (DPI)
93
Incadaterol/glycopyrronium age/indication
adult; COPD only
94
Incadaterol/glycopyrronium class
LABA/ LAMA
95
Formoterol/Glycopyrronium brand
Bevespi Aerosphere
96
Formoterol/Glycopyrronium dosage form
aerosphere (soft mist inhaler)
97
Formoterol/Glycopyrronium age/indication
Adult; COPD only
98
Formoterol/Glycopyrronium class
LABA/LAMA
99
Formoterol/Aclidinium brand
Duaklir Pressair
100
Formoterol/Aclidinium dosage form
Pressair (DPI)
101
Formoterol/Aclidinium age/indication
adult; copd only
102
Formoterol/Aclidinium class
LABA/LAMA
103
Fluticasone/Umeclidinium/Vilanterol Brand
Trelegy Ellipta
104
Fluticasone/Umeclidinium/Vilanterol dosage form
Ellipta (DPI)
105
Fluticasone/Umeclidinium/Vilanterol age/indication
Adult; Asthma or COPD
106
Fluticasone/Umeclidinium/Vilanterol class
ICS/LAMA/LABA
107
Budesonide/ Glycopyrrolate/ Formoterol Fumarate brand
Breztri Aerosphere
108
Budesonide/ Glycopyrrolate/ Formoterol Fumarate dosage form
Aerosphere (soft mist inhaler)
109
Budesonide/ Glycopyrrolate/ Formoterol Fumarate age/use
adult; COPD only
110
Budesonide/ Glycopyrrolate/ Formoterol Fumarate class
ICS/LAMA/LABA
111
Leukotriene modifiers MOA
block the production of leukotrienes = less inflammation
112
montelukast brand
singulair
113
montelukast dosage form
tablets; granule packets
114
montelukast age groups/indication
1-4,5-11, adults; asthma only
115
montelukast counseling
Minor substrate for CYP enzymes (3A4) not for acute symptom relief boxed warning for neuropsychiatric events
116
zafirlukast brand
Accolate
117
zafirlukast dosage form
Tablets
118
Montelukast class
leukotriene modifier
119
zafirlukast age/indication
5-11, adult; asthma only
120
zafirlukast counseling
1 hour before or 2 hours after meals, Major CYP substrate, minor inhibitor of CYP, at risk for bleeding
121
Zileuton brand
Zyflo CR
122
zileuton dosage form
IR and ER tablets
123
zileuton age/indication
adult only; asthma only
124
zafirlukast class
leukotriene modifier
125
zileuton counseling
Weak CYP inhibitor take with food
126
zileuton class
leukotriene modifier
127
leukotriene modifier adverse effects
neuropsychiatric events (agitation, anxiety, suicidal thinking, depression), increased hepatic transaminases - less effective than ICS/ ICS&LABA
128
theophylline
- theochron - tablets, COPD only - a methylxanthine - similiar side effects as caffeine
129
Omalizumab brand
Xolair
130
Omalizumab dosage form
prefilled syringe for injection
131
omalizumab age/indication
6-adult; asthma
132
omalizumab class/ MOA
Anti-IgE; inhibits IgE binding on mast cells and basophils; inhibits mediator release and allergic response/inflammation
133
omalizumab counseling
adverse: headache, injection site reactions, sinusitis/ upper respiratory tract infections,anaphylaxis
134
Dupilumab brand
Dupixent
135
Dupilumab dosage form
syringe for injection
136
Dupilumab; age and indication
adult; asthma
137
Dupilumab class/ MOA
Anti-IL4/IL13; reduce eosinophil trafficking, IgE reactions, mucus secretion and airway remodeling.
138
What do you need to prescribe Dupilumab?
Eosinophil count
139
Roflumilast brand
Daliresp
140
Roflumilast Dosage form
tablets
141
Roflumilast age/indication
adult; COPD only
142
Roflumilast class/MOA
phosphodiesterase-4 inhibitor- inhibits PDE-4 leading to increased cAMP
143
Roflumilast adverse effects:
Headache, weight loss, diarrhea, nausea monitor for liver function and weight.
144
Albuterol HFA Brand Name
ProAir HFA, Ventolin HFA, Proventil HFA, ProAir Respiclick, ProAir Digihaler
145
Albuterol dosage forms
HFA (most common) and Respiclick (DPI) and Nebulizer solution
146
Albuterol Age and Indication
For exacerbations, all ages
147
Albuterol HFA class
short acting beta-2 agonist
148
Albuterol Adverse effects
high heart rate/ tremor - arrythmias and tachycardia may be contraindicated
149
Levalbuterol brand
Xopenex
150
Levalbuterol dosage forms
MDI and nebulizer solution
151
Levalbuterol age/ indication
exacerbations/ all ages
152
Levalbuterol class
Short acting B2 agonist
153
Levalbuterol AE
tachycardia, tremor, hypokalemia, irritability
154
Ipatropium brand
Atrovent
155
Ipatropium dosage forms
MDI and nebulizer solution
156
Ipatropium age/indication
all; exacerbations
157
Ipatropium class
Short acting anti-cholinergics
158
Ipatropium counseling
should not be used alone or as first-line therapy; combine with SABA for asthma exacerbations AE: dry mouth, urinary retention, infection, sinusitis, bronchitis
159
Ipatropium/ Albuterol brand
Combivent respimat
160
Ipatropium/Albuterol dosage form
MDI and Nebulizer solution
161
Ipatropium/ Albuterol indication/age
all ages; asthma exacerbations
162
systemic corticosteroids used for asthma/COPD exacerbations
methylprednisolone, prednisolone, prednisone, dexamethasone, methylprednisolone acetate

Therapeutics (7 decks)

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