asthma drugs

Question 1

name 3 examples of B2 adernergic receptor antagonists?

Answer 1

salbutamol, terbutaline, salmeterol

Question 2

what is the duration of salbutamol and terbutaline?

Answer 2

30 mins, max effect 4-6 hours

Question 3

what is the duration of action of salmeterol?

Answer 3

12 hours

Question 4

what is theophylline?

Answer 4

phosphodiesterase inhibitor

Question 5

when in theophylline used?

Answer 5

used with steroid treatment when asthma response to B2 agonist is inadequate

Question 6

what are the side effects of theophylline?

Answer 6

tremor, sleep disturbance, vasodilation, anoxrexia, nausea, vomiting

Question 7

name an example of a muscarinic receptor antagonist?

Answer 7

ipratropium

Question 8

what is the duration of effect with ipratropium?

Answer 8

30 mins, max effect 3-5 hours

Question 9

what are the actions of ipatropium?

Answer 9

bronchodilation, inhibit elevated mucus secretions

Question 10

what are two exampkles of leukotriene receptor antagonist?

Answer 10

montelucast, zafirblast

Question 11

what specific types of asthma does leukotrienne receptor antagonist target?

Answer 11

excersise induced, aspirin

Question 12

what are the specific actions of leukotrienne antagonists?

Answer 12

prevent LTC4, LTD4

Question 13

what are the side effects of leukotrienne antagonists?

Answer 13

headache, GI disturbances

Question 14

name a few examples of glucocorticoids?

Answer 14

beclametasone, budsonide, fluticasone proprionate

Question 15

what are the side effects associated with glucocorticoids?

Answer 15

thrush, dysphonia

Question 16

name an example of a cromoglicate drug?

Answer 16

nedocromil sodium

Question 17

name an example of a biologic agent?

Answer 17

omalizumab

Question 18

what is the route of admin, and how often does omalizumab need to be administered?

Answer 18

sub cut every 2-3weeks