At the molecular level - Part 2 Flashcards

1
Q

Phases of the cell cycle

A
  1. Interphase

2. Miotic phase

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2
Q

Stages of mitosis

A
  1. prophase
  2. Prometaphase
  3. Metaphase
  4. Anaphase
  5. Telophase

Cytokinesis overlaps with latter stages to comple miotic pase

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3
Q

Cytokinesis

A

The division of the cytoplasm where one cell becomes 2

  • Division of cytoplasm
  • In animal cells: cell pinches in two
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4
Q

Interphase: G2

A
  • Centrosomes are duplicated
  • 2 centrosomes, each with 2 centrioles
  • Chromosomes have been duplicated
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5
Q

Prophase

A

First stage of mitosis

  • Chromosomes condense (two identical sister chromatids joined at centromere
  • Nucleoli disappear
  • Miotic spindle forms (centrosomes and microtubules)
  • Centrosomes pushed away fro each other
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6
Q

Prometaphase

A

Stge 2 of mitosis

  • Nuclear envelope fragments
  • Each of two chromatids now have a kinetochore (a protein structure at the centromere)
  • Microtubules attach to kinetochore
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7
Q

Metaphase

A

Stage 3 of mitosis

  • Centrosomes at oppsote poles of cell
  • Chromosomes at metaphase plate
  • Plane equidistant between two poles
  • Centromeres at metaphase plate
  • Kinetochores attached to microtubules from opposite poles
  • Miotic spindle
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8
Q

Anaphase

A

Stage 4 of mitosis

  • Two sister chromatids are pulled apart
  • Each chromatid becomes a chromosome
  • Daughter chromosomes moved to oppsodite ends of cell have complete copies of chromosomes
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9
Q

Telophase

A

Stage 5 of mitosis

  • 2 daughter nuclei form
  • Nucleoli reappear
  • Chromosomes decondense
  • Spindle breaks down
  • Mitosis is finished
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10
Q

Cell cycle: animal vs plants cells

A
  1. Centrosomes are not necessary for miotic spindle to form
    - Plant cells do not have them, but still have miotic spindle
    - Animal cells with destroyed centrosomes form miotic spindle too
  2. Cytokinesis
    - In animal cells: It occurs by cleavage (microfilaments contract until cell splits in two)
    - In plant cells: No cleavage furrow; cell plate produced by vesicles from Golgi during telophase turn into cell walls
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11
Q

Cell cycle in bacteria

A

Binary fission

  • Type of reproduction prokaryotes undergo
  • Cell grows 2x its size, then divides to make 2 cells
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12
Q

Steps of binary fission

A
  1. Replication begins
  2. One copy of origin of replication moves to opposide end of cell
  3. The replication continues
  4. When replication is done, the plasma membrane pinches inward and a new cell wall is made
  5. Result in two daughter cells
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13
Q

Meiosis

A
  • How sex cells (gametes) are formed (sperm and eggs)
  • Pffspring not identical to either parent and are different of each other
  • There are inherited similarities, but also variation
  • Variation allows breeding of plants and animals with different characteristics
  • Evolution by natural selection works on this variation well
  • Duplication of chromosomes followed by 2 consecutive cell divisions
  • results in 4 daughter cells
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14
Q

Stages of meiosis

A
  1. Prophase 1
  2. Metaphase 1
  3. Anaphase 1
  4. Telophase 1
  5. Prophase 2
  6. Metaphase 2
  7. Anaphase 2
  8. Telophase 2
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15
Q

Prophase 1

A
  • Chromosomes condense
  • Homologues pair up and align gene by gene
  • Synapsis occurs
  • Crossing over
  • Synapsis ends
  • Each homologous pair has at least 1 chiasmata
  • Homologous pairs move toward metaphase
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16
Q

Synapsis

A
  • Paired homologues become physically connected and form tetrads
17
Q

Chiasmata

A

Wherever a crossover has occur

Where you had a breakage and reattachment of DNA

18
Q

Metaphase 1

A
  • Pairs of homologues at metaphase plate (one chromosome pair of each tetrad is facing different poles)
  • Both chromatids of one homologue is attached to kinetochore microtubules from one pole; the others attached to microtubules on the opposite end
19
Q

Anaphase 1

A
  • Homologues separate and move toward opposite poles

- Chromatids are still attached and move as a unit

20
Q

Telophase 1

A
  • Each half of cell has complete haploid set of duplicated chromosomes
  • Each chromosome made 2 sister chromatids
  • One or both chromatids include regions of nonsister chromatid DNA
  • Cytokinesis occurs
  • 2 haploid daughter cells are born
21
Q

Prophase 2

A
  • Spindle froms

- Chromosomes (each composed of 2 sister chromatids) move toward metaphase 2

22
Q

Metaphase 2

A
  • Chromosomes at metaphase plate

- Two sister chromatids of each chromosome are genetically identical due to crossing over

23
Q

Anaphase 2

A
  • Chromatids separate and move to opposite poles as individual chromosomes
24
Q

Telohase 2

A
  • Nuclei from
  • Chromosomes decondense
  • Cytokinesis occurs
  • 4 genetically distinct daughter cells are formed
25
Q

What is the original source of genetic variation?

A

Mutation

26
Q

Processes responsible for genetic mutation

A
  1. Independent assortment of chromosomes
  2. Crossing over
  3. Random fertilization
27
Q

Recombinant chromosomes

A

Chromosomes that carry genes from 2 different parents