Auditory System B&B Flashcards

1
Q

which of the inner ear bones pushes on the fluid-filled cochlea?

A

stapes - (smallest) pushes on fluid-filled cochlear, which stimulates hair cells in the Organ of Corti

[others are malleus and incus]

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

where do auditory nerve impulses go after being electrically converted in the inner ear (at the Organ of Corti)?

A

carried by cochlear nerve (CN VIII) to the cerebellopontine angle (in the lateral pons)

from there, connect to many structures including superior olivary nucleus, trapezoid body, lateral lemniscus, inferior colliculus, medial geniculate body, transverse temporal gyri of Heschl, etc

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

a brainstem lesion with hearing loss can most likely be located to where exactly?

A

cerebellopontine angle in the lateral pons - this is where auditory impulses are carried to by the cochlear nerve of CN VIII

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

which of the following is NOT an example of conductive hearing loss?
a. obstruction (wax)
b. otosclerosis
c. cochlear nerve failure
d. otitis media

A

c. cochlear nerve failure (acoustic neuroma) - this is sensorineural hearing loss

obstruction, otosclerosis (bony overgrowth of stapes), and otitis media are examples of conductive hearing loss - sound waves can’t be converted to nerves signals

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

presbycusis

A

age-related hearing loss due to degeneration of the Organ of Corti

slow developing sensorineural hearing loss

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

how does the Weber Test evaluate hearing?

A

place vibrating tuning fork on bridge of forehead, nose, or teeth

ask patient if they can hear the vibrations in both ears - should be equal on both sides

in CONDUCTIVE hearing loss, sound will be LOUDER in BAD ear because there is no background noise from the outside

in sensorineural hearing loss, sound will be quieter in bad ear because there is no CN VIII ability to sense vibration

[so you need to know which ear has hearing defect]

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Your patient presents with complaint of hearing loss. You place a vibrating tuning fork on the bridge of their forehead and ask which side sounds louder. Your patient says it sounds louder on the L side. What type of hearing loss do they have?
a. conductive
b. sensorineural

A

(Weber Test)

trick question - you cannot tell without more information!!

in CONDUCTIVE hearing loss, sound will be LOUDER in BAD ear because there is no background noise from the outside

in sensorineural hearing loss, sound will be quieter in bad ear because there is no CN VIII ability to sense vibration

so you need to know which ear has hearing defect!!

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

how does the Rinne Test evaluate hearing?

A

place vibrating tuning fork first on mastoid bone (behind ear) to test bone conduction (BC) … wait until patient says they no longer hear it, then move tuning fork to just outside ear to test air conduction (AC) … ask if the patient can still hear

normal = they still hear, AC>BC

conductive hearing loss = patient cannot hear, BC>AC

sensorineural hearing loss = patient can still hear, but both AC and BC are reduced (but AC>BC)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what type of hearing loss is the Rinne Test best at detecting?

A

conductive loss

place vibrating tuning fork first on mastoid bone (behind ear) to test bone conduction (BC) … wait until patient says they no longer hear it, then move tuning fork to just outside ear to test air conduction (AC) … ask if the patient can still hear

normal = they still hear, AC>BC

conductive hearing loss = patient cannot hear, BC>AC

sensorineural hearing loss = patient can still hear, but both AC and BC are reduced (but AC>BC)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what becomes damaged in long-term noise exposure (musicians), and what type of sound is lost first?

A

damage to ciliated hair cells of Organ of Corti

high-frequency hearing is lost first (birds chirping)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

within what portion of the temporal bone is the auditory and vestibular apparatus located?

A

petrous portion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

the external ear (pinna + external ear canal) is derived from the ______ pharyngeal cleft

the auricle is derived from swellings/hillocks on the _____ pharyngeal arches

the tympanic membrane is derived from fusion of the ectoderm of the _____ pharyngeal cleft and the endoderm of the _____ pharyngeal pouch

A

the external ear (pinna + external ear canal) is derived from the FIRST pharyngeal CLEFT

the auricle is derived from swellings/hillocks on the FIRST and SECOND pharyngeal ARCHES

the tympanic membrane is derived from fusion of the ectoderm of the FIRST pharyngeal CLEFT and the endoderm of the FIRST pharyngeal POUCH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

which ossicle (middle ear bone) is attached to the inner surface of the tympanic membrane?

A

malleus

[which attaches to incus, which attaches to stapes on the oval window of the inner ear]

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what are the 2 skeletal muscles of the inner ear?

A
  1. tensor tympani: innervated by CN V3, attaches to malleus
  2. stapedius: innervated by CN VII, attaches to stapes

contracting reduces amplitude of vibration of the tympanic membrane and ossicles (response to loud sound to protect cochlear hair cells)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

lesion of the CN ____ may causes hyperacusis, an increased perception of loudness because of the loss of the action of the stapedius.

A

lesion of the facial nerve (VII) may causes hyperacusis, an increased perception of loudness because of the loss of the action of the stapedius.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

allows for the equalization of air pressure between the middle ear cavity and the environmen

A

auditory (Eustachian) tube: connects middle ear to nasopharynx

also provides pathway for spread of infection from pharynx to middle ear!

17
Q

middle ear, the auditory tube, and the mastoid air cells are derived from the _____ pharyngeal _______ and are lined by endodermal epithelium

A

middle ear, the auditory tube, and the mastoid air cells are derived from the FIRST pharyngeal POUCH and are lined by endodermal epithelium

all communicate with each other, therefore allowing spread of infection

18
Q

ossicles and muscles of the middle ear are derived from pharyngeal [clefts/arches]

A

arches:

malleus, incus (neural crest), tensor tympani (mesoderm) - FIRST pharyngeal arch

stapes (neural crest), stapedius (mesoderm) - SECOND pharyngeal arch

19
Q

what is/are the organ/s for audition vs vestibular sensation?

A

cochlea: organ for audition, contains Organ of Corti (cochlear hair cells are found here)

semicircular canals (3), utricle, saccule: organs for vestibular sensation, contains maculae (vestibular hair cells are found here)

20
Q

what is the function of each of the following organs for vestibular sensation:
a. 3 semicircular canals
b. utricle
c. saccule

A

a. 3 semicircular canals: lie in 3 planes of space and detect rotational movements of the head

b. utricle: detects linear motion in horizontal plane

c. saccule: detects linear motion in vertical plane

21
Q

The inner ear is derived from the ______, a thickening of the skin ectoderm

A

The inner ear is derived from the otic placode, a thickening of the skin ectoderm

22
Q

most frequent diagnosis in sick children visiting the ped’s office and most common reason for administration of antibiotics in children

A

acute otitis media: bacterial infection of middle ear

otalgia (ear pain) is most common complaint (ear tugging), nonspecific symptoms in infants

23
Q

what are some risk factors for acute otitis media (AOM)?

A

[bacterial infection of middle ear]

  1. rates peak 6-18 months
  2. day care
  3. lack of breast feeding
  4. tobacco smoke/ pollution
  5. pacifier use
24
Q

how does immature anatomy contribute to development of acute otitis media?

A

Eustachian (auditory) tube is shorter, more horizontal, more compliant

allows for easier colonization/ obstruction

25
Q

what are the most common bacterial causes of acute otitis media? (3)

A
  1. streptococcus pneumoniae
  2. Haemophilus influenzae
  3. moraxella catarrhalis
26
Q

how does the tympanic membrane appear in patients with acute otitis media?

A
  1. whitish discoloration
  2. bulging
  3. marked erythema
27
Q

Describe the clinical features of Meniere Disease (3)

A
  1. fluctuating hearing loss (low frequency)
  2. episodic rotational vertigo
  3. tinnitus (roaring seashell)
28
Q

Meniere Disease

A

Ménière disease is a disorder caused by build of fluid in the chambers in the inner ear. It causes symptoms such as vertigo, nausea, vomiting, loss of hearing, ringing in the ears, headache, loss of balance, and sweating

People with Ménière’s disease usually experience some or all of these symptoms during sudden attacks, which typically last around two to three hours,

29
Q

what syndrome presents similarly to Meniere Disease and is far more common?

A

Ménière disease is a disorder caused by build of fluid in the chambers in the inner ear. It causes symptoms such as vertigo, nausea, vomiting, loss of hearing, ringing in the ears, headache, loss of balance, and sweating

vestibular migraines present similarly and are more common

30
Q

Waardenburg Syndrome (WS1)

A

AD or AR mutation in PAX3 transcription factor —> sensorineural, pre-lingual hearing loss + changes in pigmentation of the hair, skin, and eyes (pale)

mild-profound hearing loss, not usually progressive

31
Q

Pendred Syndrome

A

mutation in PENDRIN anion transporter —> sensorineural deafness, enlarged vestibular aqueduct, shortened cochlea, goiter (euthyroid or mild hypothyroidism)

32
Q

describe the auditory symptoms/effects of osteogenesis imperfecta

A

conductive hearing loss in 2nd/3rd decade due to stapes fixation or fracture

[recall presentation includes frontal bossing, low set ears, blue sclerae]