Autoimmunity And Transplantation

Question 1

What’s the significance of immunological tolerance?

Answer 1

Question 2

Contrast central and peripheral tolerance

Answer 2

Question 3

Contrast central tolerance of T cells

Answer 3

Question 4

Contrast positive and negative selection

Answer 4

Question 5

How are self-antigens expressed in the thymus?

Answer 5

Question 6

What is autoimmune polyglandular syndrome?

Answer 6

Question 7

What are tolerogens?

Answer 7

Question 8

What happens when tolerance fails?,

Answer 8

Question 9

What are the causes of autoimmunity?

Answer 9

Question 10

What causes MHC locus disease?

Answer 10

Question 11

What are immune privileged sites?

Answer 11

Question 12

What are the significance of CTLA-4 for autoimmunity?

Answer 12

Question 13

Which immune reactions can lead to autoimmunity?

Answer 13

Type 2,3, and 4

Question 14

What is type 2 cytotoxicity?

Answer 14

Question 15

What are the non-cytotoxic type 2 types of autoimmunity?

Answer 15

Question 16

How is pernicious anemia a type 2 non-cytotoxic aytiimmunity?

Answer 16

Question 17

How are antibodies involved in type 2 autoimmune/hypersensitivity?

Answer 17

Question 18

What is good pastures?

Answer 18

Question 19

What hypersensitivity type are systemic autoimmune diseases?

Answer 19

Question 20

What is lupus?

Answer 20

Question 21

What is the use of antinuclear antibody screening

Answer 21

Question 22

What is rheumatoid arthritis?b

Answer 22

Question 23

What are assoc8ated with rheumatoid association?

Answer 23

Question 24

Describe type 4 autoimmune diseases

Answer 24

Question 25

What is Hashimoto’s thyroiditis?

Answer 25

Question 26

What type of hypersensitivity leads to type 2 diabetes

Answer 26

Question 27

What is the impact of T cells?

Answer 27

Question 28

What are the common types of hypersensitivity?

Answer 28

Question 29

Summarize this deck

Answer 29