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My CPR > Autonomic Drug List > Flashcards

Autonomic Drug List Flashcards

1
Q

AchE inhibitor

A

Pyridostigmine

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2
Q

Muscarinic antagonist

A

Atropine

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3
Q

Adrenergic agonists

A 
Clonidine
Dobutamine
Dopamine
Epinephrine
Isoprenternol 
Methyldopa
Midrodrine 
Norepinephrine
Phenylephrine
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4
Q

Adrenergic antagonists

A 
Carvedilol
Doxazosin
Labetalol
Metroprolol
Phentolamine
Phenoxybenzamine
Propranolol
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5
Q

Pyridostigmine

A
  • Reversible AchE inhibitor
  • treatment of neurogenic orthostatic hypotension or myasthenia gravis
  • SAE: Respiratory depression, bradycardia, lacrimation, diarrhea
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6
Q

Atropine

A
  • Non-selective muscarinic antagonist
  • Reversal of vagal bradycardia, antidote for cholinesterase inhibitor toxicity
  • SAE: tachycardia
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7
Q

Clonidine

A
  • selective agonist at alpha 2 receptors in CNS, this results in decreased sympathetic outflow
  • hypertension
  • postural hypotension, bradycardia, sedation, dry mouth
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8
Q

Dobutamine

A
  • beta 1 selective agonist
  • increased cardiac output in acute heart failure, stress testing
  • SAE: Tachycardia
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9
Q

Dopamine

A
  • dopamine agonist (duh!), alpha, beta agonist
  • shock, sometimes used in acute heart failure
  • SAE: tachycardia, vasoconstriction, local necrosis
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10
Q

Epinephrine

A
  • adrenergic agonist
  • emergency treatment of cardiac arrest, anaphylaxis
  • SAE: arrythmia, local necrosis
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11
Q

Isoprenterolol

A
  • non-selective beta-adrenergic agonist
  • limited use in bradycardia
  • SAE: tachycardia, hypotension
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12
Q

Methyldopa

A
  • converted to alpha-methylnorepinephrine which acts as a selective agonist at alpha-2 receptors in the CNS, resulting in reduced symphathetic outflow
  • limited use as an anti-hypertensive in pregnancy
  • SAE: postural hypotension, bradycardia, sedation, dry mouth
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13
Q

Midodrine

A
  • alpha 1 selective agonist
  • chronic orthostatic hypotension
  • SAE: hypertension, bradycardia
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14
Q

Norepinephrine

A
  • adrenergic agonist
  • restoration of BP in acute hypotensive states
  • SAE: arrhythmia, extravasation necrosis
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15
Q

Phenylephrine

A
  • alpha adrenergic agonists
  • test of baroreceptor reflex, short term vasoconstriction, decongestant
  • SAE: hypertension, bradycardia
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16
Q

Carvedilol

A
  • antagonist at alpha 1 and beta receptors; biased agonist at beta-1 receptor
  • hypertension, heart failure
  • SAE: bradycardia, broncho-constriction
17
Q

Doxazosin

A
  • alpha-1 selective antagonist
  • benign prostatic hyperplasia, rarely hypertension
  • SAE: orthostatic hypotension
18
Q

Labetalol

A
  • antagonist at alpha 1 and beta receptors
  • hypertension
  • SAE: bradycardia, broncho-constriction
19
Q

Metoprolol

A
  • beta 1 selective antagonist
  • hypertension, heart failure
  • SAE: bradycardia, broncho-constriction
20
Q

Phentolamine

A
  • non-selective alpha adrenergic agonist
  • treatment of extravasation of adrenergic agonists
  • SAE: orthostatic hypotension, tachycardia, nasal congestion
21
Q

Phenoxybenzamine

A
  • non-selective covalent (long acting) alpha antagonist
  • pheochromocytoma
  • SAE: orthostatic hypotension, tachycardia, nasal congestion
22
Q

Propranolol

A
  • non-selective beta adrenergic receptor antagonist
  • angin, arrhythmias, tremor, stage fright, migraine, hypertension
  • SAE: bradycardia, broncho-constriction
23
Q

What is the effect of alpha blockers?

A

They prevent NE from binding and

My CPR (6 decks)

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