autonomic drugs

Question 1

direct muscarinic agonists

Answer 1

bethanechol, carbachol, pilocarpine, methacholine

Question 2

treatment of post op ileum and neurogenic bladder

Answer 2

bethanechol and neostigmine

Question 3

muscarinic agonists for glaucoma

Answer 3

pilocarpine and carbachol

Question 4

anticholinesterases

Answer 4

neostigmine, pyridostigmine, physostigmine, donepezil, rivastigmine, galantamine, edrophonium

Question 5

myasthenia gravis treatment

Answer 5

pyridostigmine

Question 6

treatment of anticholinergic toxicity

Answer 6

physostigmine

Question 7

diagnosis of myasthenia gravis

Answer 7

edrophonium

Question 8

atropine

Answer 8

muscarinic antagonist used to treat bradycardia and for ophthalmic applications

Question 9

Tx motion sickness

Answer 9

scopolamine

Question 10

glycopyrrolate

Answer 10

antimuscarinic used preoperatively to reduce secretions

Question 11

ipratropium and tiotropium

Answer 11

antimuscarinics used to treat asthma and COPD

Question 12

benztropine

Answer 12

antimuscarinic for parkinson disease

Question 13

reduce urgency in cystits

Answer 13

oxybutynin, darifenacin, solifenacin, tolterodine, fesoterodine, trospium

Question 14

epinephrine

Answer 14

beta > alpha at low doses

at high doses, alpha effects predominate

Question 15

norepinephrine

Answer 15

alpha1 > alpha2 > beta1

used in hypotension (e.g. sepsis)

Question 16

isoproterenol

Answer 16

Beta1 = beta2

Question 17

dopamine

Answer 17

D1 = D2 > Beta > alpha
alpha predominates at high doses
used in CHF to increase contractility and HR

Question 18

phenylephrine

Answer 18

alpha1 > alpha 1

Question 19

albuterol

Answer 19

Beta2 > Beta1

used for acute asthma

Question 20

salmeterol

Answer 20

Beta2 > Beta1

used for chronic asthma and COPD

Question 21

terbutaline

Answer 21

Beta2 > Beta1

used to decrease uterine contractions

Question 22

clonidine

Answer 22

alpha 2 agonist

used in hypertensive urgency - causes significant rebound HTN

Question 23

methyldopa

Answer 23

alpha 2 agonist

used for hypertension in pregnancy

Question 24

phenoxybenzamine

Answer 24

irreversible nonselective alpha block

treatment of pheochromocytoma

Question 25

phentolamine

Answer 25

reversible nonselective alpha block

Question 26

alpha1 blockers

Answer 26

end in "osin"

Question 27

alpha1 blocker use and toxicity

Answer 27

BPH and HTN | cause 1st dose hypotension and rebound tachycardia

Question 28

tamsulosin

Answer 28

alpha-1AD selective (specific to prostate) for treatment of BPH

Question 29

alpha 2 blocker

Answer 29

mertazapine

Question 30

beta-1 selective antagonists

Answer 30

end in olol, start with A-M

Question 31

non-selective beta blockers

Answer 31

end in olol; start with N-Z

Question 32

carvedilol and labetalol

Answer 32

alpha 1 and beta 1 block -- decreases HR and BP via peripheral vasodilation

Question 33

who should you not use beta blockers in

Answer 33

diabetics, cocaine addicts, asthmatics, and COPD

Question 34

acebutolol and pindolol

Answer 34

weak beta 1 and 2 agonists - because they are so weak, they act as blockers; used in patients with HTN + bradycardia