autonomic drugs (to memorize the list!) Flashcards

This is JUST for memorizing the drugs, their class, and what receptors they activate. More info in the other slide decks!!! (52 cards)

1
Q

What are cholinergic agonists?

A

Substances that activate cholinergic receptors

Examples include acetylcholine, muscarine, pilocarpine, and bethanechol.

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2
Q

List three examples of cholinergic agonists.

A
  • Acetylcholine (M/N)
  • Muscarine (M)
  • Pilocarpine (M)
  • Bethanechol (M)
  • Physostigmine (AChE inhibitor)
  • Echothiophate (AChE inhibitor)
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3
Q

What is the function of adrenergic agonists?

A

Substances that activate adrenergic receptors

These can affect alpha and beta receptors.

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4
Q

List three examples of adrenergic agonists.

A
  • Norepinephrine (α1, α2, β1)
  • Epinephrine (α1, α2, β1, β2)
  • Phenylephrine (α1)
  • Clonidine (α2)
  • Dobutamine (β1)
  • Isoproterenol (β1, β2)
  • Albuterol (β2)
  • Tyramine (indirect)
  • Amphetamine (indirect)
  • Cocaine (indirect)
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5
Q

What are cholinergic antagonists?

A

Substances that block cholinergic receptors

An example is atropine.

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6
Q

List an example of a cholinergic antagonist.

A
  • Atropine (M)
  • D-Tubocurarine (NM)
  • Trimethaphan (NN)
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7
Q

What are adrenergic antagonists?

A

Substances that block adrenergic receptors

They can selectively block alpha or beta receptors.

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8
Q

List three examples of adrenergic antagonists.

A
  • Prazosin (α1)
  • Yohimbine (α2)
  • Metoprolol (β1)
  • Propranolol (β1, β2)
  • Butoxamine (β2)
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9
Q

Fill in the blank: Acetylcholine is a __________ agonist.

A

[cholinergic]

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10
Q

True or False: Epinephrine is an adrenergic agonist.

A

True

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11
Q

What is the role of AChE inhibitors?

A

They prevent the breakdown of acetylcholine, increasing its availability

Examples include physostigmine and echothiophate.

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12
Q

Fill in the blank: The drug __________ is a selective β1 adrenergic agonist.

A

[dobutamine]

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13
Q

What kind of drug is acetylcholine? What receptor(s) does it activate?

A

Cholinergic agonist (M/N)

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14
Q

What kind of drug is muscarine? What receptor(s) does it activate?

A

Cholinergic agonist (M)

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15
Q

What kind of drug is pilocarpine? What receptor(s) does it activate?

A

Cholinergic agonist (M)

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16
Q

What kind of drug is bethanechol? What receptor(s) does it activate?

A

Cholinergic agonist (M)

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17
Q

What kind of drug is nicotine? What receptor(s) does it activate?

A

Cholinergic agonist (N)

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18
Q

What kind of drug is physostigmine? What receptor(s) does it activate?

A

Cholinergic agonist (AChE inhibitor)

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19
Q

What kind of drug is echothiophate? What receptor(s) does it activate?

A

Cholinergic agonist (AChE inhibitor)

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20
Q

What kind of drug is atropine? What receptor(s) does it activate?

A

Cholinergic antagonist (M)

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21
Q

What kind of drug is Trimethaphan? What receptor(s) does it activate?

A

Cholinergic antagonist (Nn)

22
Q

What kind of drug is D-Tubocurarine? What receptor(s) does it activate?

A

Cholinergic antagonist (Nm)

23
Q

What kind of drug is norepinephrine? What receptor(s) does it activate?

A

Adrenergic agonist (a1, a2, b1)

24
Q

What kind of drug is epinephrine? What receptor(s) does it activate?

A

Adrenergic agonist (a1, a2, b1, b2)

25
What kind of drug is phenylephrine? What receptor(s) does it activate?
Adrenergic agonist (a1)
26
What kind of drug is clonidine? What receptor(s) does it activate?
Adrenergic agonist (a2)
27
What kind of drug is dobutamine? What receptor(s) does it activate?
Adrenergic agonist (b1)
28
What kind of drug is isoproterenol? What receptor(s) does it activate?
Adrenergic agonist (b1, b2)
29
What kind of drug is albuterol? What receptor(s) does it activate?
Adrenergic agonist (b2)
30
What kind of drug is tyramine? What receptor(s) does it activate?
Adrenergic agonist (indirect)
31
What kind of drug is amphetamine? What receptor(s) does it activate?
Adrenergic agonist (indirect)
32
What kind of drug is cocaine? What receptor(s) does it activate?
Adrenergic agonist (indirect)
33
What kind of drug is prazosin? What receptor(s) does it activate?
Adrenergic antagonist (a1)
34
What kind of drug is yohimbine? What receptor(s) does it activate?
Adrenergic antagonist (a2)
35
What kind of drug is metoprolol? What receptor(s) does it activate?
Adrenergic antagonist (b1)
36
What kind of drug is propranolol? What receptor(s) does it activate?
Adrenergic antagonist (b1, b2)
37
What kind of drug is butoxamine? What receptor(s) does it activate?
Adrenergic antagonist (b2)
38
What are the 4 cholinergic agonists that activate M receptors?
- acetylcholine (M/N) - muscarine (M) - pilocarpine (M) - bethanechol (M)
39
What are the 2 cholinergic agonists that activate N receptors?
- nicotine (N) - acetylcholine (M/N)
40
What are the 2 cholinergic agonists that are AChE inhibitors?
- physostigmine - echothiophate
41
What is the cholinergic antagonist that activates M receptors
- Atropine
42
What is the cholinergic antagonist that activates Nm receptors? | Nm = Nicotinic (NM) receptors at the neuromuscular junction
- D-Tubocurarine
43
What is the cholinergic antagonist that activates Nn receptors? | Nn = Nicotinic (NN) receptors in autonomic ganglia
- Trimethaphan
44
What are the 3 indirect adrenergic agonists?
- tyramine - amphetamine - cocaine
45
What are the 3 adrenergic agonists that activate a1 receptors?
- norepinephrine - epinephrine - phenylephrine
46
What are the 3 adrenergic agonists that activate a2 receptors?
- norepinephrine - epinephrine - clonidine
47
What are the 4 adrenergic agonists that activate b1 receptors?
- norepinephrine - epinephrine - dobutamine - isoproterenol
48
What are the 3 adrenergic agonists that activate b2 receptors?
- epinephrine - albuterol - isoproterenol
49
What is the adrenergic antagonist that activates a1 receptors?
- prazosin
50
What is the adrenergic antagonist that activates a2 receptors?
- yohimbine
51
What are the 2 adrenergic antagonists that activate b1 receptors?
- metoprolol - propranolol
52
What are the 2 adrenergic antagonists that activate b2 receptors?
- propranolol - butoxamine