Autonomic nervous system Flashcards

(61 cards)

1
Q

what is the ANS

A

involuntary efferent division of the PNS

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2
Q

what does the ANS control

A

muscles and glands

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3
Q

is the autonomic nervous system voluntary or involuntary

A

involuntary

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4
Q

what is the ANS activated by

A

centers in the spinal cord, brain stem, and hypothalamus

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5
Q

what part of the nervous system controls most visceral function in the body

A

ANS

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6
Q

autonomic nerve pathway

A

preganglionic fiber synapses with the cell body of the second neuron which lies within a ganglion
post ganglionic fiber innervates effector organ

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7
Q

cholinergic receptors

A

nicotinic receptors that are found in the postganglionic cell bodies in all autonomic ganglia

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8
Q

what do cholingergic receptors respond to

A

Ach released from both sympathetic and parasympathetic preganglionic fibers and adrenal medulla

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9
Q

what neurotransmitters are released in preganglionic fibers in the sympathetic and parasympathetic NS

A

acetylcholine

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10
Q

what does acetylcholine bind to

A

muscarinic or nicotinic receptors

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11
Q

parasympathetic postganglionic fibers release what NT

A

acetylcholine

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12
Q

what are cholinergic fibers

A

release acetylcholine a their ending

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13
Q

sympathetic post ganglionic fibers release what NT

A

norepinephrine

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14
Q

what are sympathetic post ganglionic fibers called

A

adrenergic fibers

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15
Q

where is norepinephrine released from in the sympathetic nervous system

A

adrenal medulla in small amounts

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16
Q

what does epinephrine bind to

A

alpha and beta receptors

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17
Q

what type of receptor does epinephrine bind to

A

beta 2

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18
Q

what type of receptor does norepinephrine bind to

A

alpha and beta 1

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19
Q

what type of receptor does Ach bind to in the parasympathetic pathway

A

muscarinic

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20
Q

what type of receptor does Ach bind to in the sympathetic pathway

A

nicotinic (skeletal muscle)

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21
Q

what are some of the autonomic effectors

A

smooth and cardiac muscle
some endocrine and exocrine glands
some adipose tissue

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22
Q

what type of glands are the adrenal medulla

A

endocrine

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23
Q

what is the outer part of the adrenal gland called

A

adrenal cortex

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24
Q

what is the inner portion of the adrenal medulla called

A

adrenal medulla

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25
the adrenal medulla is a modified part of the sympathetic ganglion that does not give rise to what
post ganglionic fibers -must go through adrenal medulla which released epinephrine into the blood which goes to the effector
26
what does the adrenal gland do upon stimulation by the preganglionic fiber from the CNS
secretes catecholamines into the blood
27
what percentage of hormone output from the adrenal gland is norepinephrine
20%
28
what percentage of hormone output from the adrenal gland is epinephrine
80%
29
sympathetic dominance
fight or flight promotes response that prepares the body for strenuous physical activity in emergency or stressful situation
30
adrenergic receptors (sympathetic) major classes (two)
alpha and beta
31
norepinephrine mainly excited which adrenergic receptor
alpha( but can excite beta to lesser extent)
32
epinephrine excites which adrenergic receptor
both alpha and beta equally
33
what does beta 1 activation help with
increasing heart rate and contractility in the heart increasing stroke volume and cardiac output
34
what does activation of beta 2 help with
bronchiodilation in the lungs
35
what does activation of alpha 1 help with
smooth muscle contraction and glycogenolysis cause vasoconstriction
36
parasympathetic dominance
dominated in quiet, relaxed situations -body has housekeeping activities -rest and digest bodily functions
37
muscarinic cholinergic receptors are found in which system
parasympathetic
38
are visceral organs innervated by sympathetic or parasympathetic nerve fibers
both
39
what is dual innervation
innervation of a single organ by both branches of the autonomic nervous system
40
when both systems (para and sympathetic) are active what is that called
tone *different from dominance
41
when does system dominance occur
when fibers rate of firing to an organ increases above tone level
42
autonomic neuropathy or dysautonomia
nerves of the ANS are damaged and causes autonomic system dysfunction
43
what are some effects of dysautonomia
blood pressure, temp control, digestion, bladder function, sexual function, exercise intolerance, sweating problems
44
what can be the cause of dysautonomia
diabetes (neuropathy) amyloidosis autoimmune diseases medications (chemo drugs) inherited disorders (familial dysautonomia)
45
what is amyloidosis
irregular protein buildup in organs
46
Horner syndrome
rare disorder resulting from interruption of the pre or postganglionic sympathetic innervation to the face
47
what is the cause or Horner syndrome
injury to the nerves, injury to the carotid artery, stroke or lesion in the brainstem
48
what is the hallmark of Horner syndrome
triad of reduced sweating (anhidrosis), drooping eyelids (ptosis), and constricted pupils (miosis)
49
what is the treatment for Horner syndrome
there is no specific pharmacologic treatment
50
autonomic agonsit
binds to the neurotransmitters receptor and causes the same response the neurotransmitter would
51
natural agonists
endorphins neurotransmitters
52
agonist drug examples
nicotine morphine heroin LSD (lysergic acid diethlamide)
53
autonomic antagonist
binds with the receptor preventing the neurotransmitter from binding and causing a response
54
examples of autonomic antagonist
atropine, metoprolol, prazosin, antibodies for myasthenia gravis
55
atropine
blocks the effects of Ach at the muscarinic receptor but doesn't affect nicotinic receptors
56
metroprolol
selectively blocks beta 1 receptors
57
prazosin
selectively blocks alpha 1 receptors
58
importance of the vagus nerve
sends signals from the brain to all other organs in the body and is in constant communication with heart lungs and gut
59
what is the vagus nerve responsible for
regulating stress response
60
what does lower vagal tone indicate
higher levels of anxiety and depression
61
the ability to change vagal tone can influence what
our mental health