synaptic transmission Flashcards

(38 cards)

1
Q

how is information transmitted through chemical messengers

A

neurotransmitters

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2
Q

what is the main excitatory neurotransmitter

A

glutamate

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3
Q

where is glutamate releases

A

sensory neurons in the cerebral cortex

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4
Q

how much glutamate is required to excite neighboring cells

A

a small amount

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5
Q

all glutamate released from the cell is picked up by what

A

glutamate transporter molecules

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6
Q

what is the main inhibitory neurotransmitter

A

GABA

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7
Q

what is another name for GABA

A

gamma aminobutyric acid

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8
Q

where is GABA released

A

neurons of the spinal cord, cerebellum, basal ganglia

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9
Q

what does GABA do

A

reduce activity in the CNS, produce a calming effect

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10
Q

abnormally low levels of GABA can lead to what

A

anxiety

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11
Q

is dopamine excitatory or inhibitory

A

both

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12
Q

where is dopamine released

A

substantia nigra

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13
Q

what does dopamine play a role in

A

brains reward system

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14
Q

what does dopamine inhibit the release of

A

prolactin

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15
Q

dopamine brings up feelings of

A

pleasure and wakefulness

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16
Q

what does dopamine coordinate in the brain

A

voluntary movement

17
Q

epinephrine is responsible for the bodies what

A

fight or flight response

18
Q

where is epinephrine released

A

chromaffin cells in the adrenal medulla

19
Q

is epinephrine excitatory or inhibitory

20
Q

is serotonin inhibitory or excitatory

21
Q

where is serotonin released

A

neurons of the brainstem and the GI tract

22
Q

what does serotonin do

A

GI tract - release feelings of satisfaction after eating
brain - influences mood, promotes feeling of wellbeing and happiness
regulates body temp, sleep cycle, pain perception

23
Q

is acetylcholine excitatory or inhibitory

24
Q

where is acetylcholine released

A

motor neurons, basal ganglia, pre-ganglionic neurons of ANS, postganglionic neurons of the PNS, postganglionic neurons of sympathetic nervous system (innervates sweat glands)

25
what does acetylcholine directly affect
muscles
26
what does acetylcholine cause
muscle to contract by working at the NMJ
27
what does acetylcholine play a role in
memory and cognition
28
Alzheimer's disease is caused by a lack of what neurotransmitter
acetylcholine
29
what characterizes alzheimers
learning and memory impairments
30
depression is caused by a lack of what neurotransmitter
dopamine, serotonin
31
schizophrenia is caused by an excess of what neurotransmitter
dopamine in the frontal lobe
32
myasthenia gravis is caused by an impairment of what neurotransmitter
acetylcholine in the synapse
33
Parkinson's disease is caused by a deficiency in what neurotransmitter
dopamine related to substantia nigra
34
what can change ion permeability
neurotransmitters
35
how do ESPS and ISPS interact
the postsynaptic neuron adds the sum together and decides whether to fire an action potential or not
36
temporal summation
summing of several ESPS occurring very close together in time by a single presynaptic neuron
37
spatial summation
summing of several ESPS occurring simultaneously from several presynaptic neurons
38
can action potentials or graded potentials be summated
graded action potentials are all or nothing responses