autonomic nervous system Flashcards
(10 cards)
what is the autonomic nervous systum apart of
and what it is in contrast to
part of PNS
-in contrast with somatic nervous system
difference between somatic and autonomic nervous system
somatic is volutary (skeletal) and autonomic is unvoluntary (cardiac, smooth muscle). maintaining homeostasus, heart rate ect.
describe the 3 divisions of autonomic nervous systum
1) sympathetic
2) parasynpathetic
3) enternic
1) ‘fight or flight’
2) ‘rest and digest’
3) ‘second brain’ independently controls the GI tract. but still comunicates with sympathetic and parasynpathetic system. controls peristalis and secretion.
describe the structural difference between somatic and autonomic neuron
somatic= single neuron pathway
autonomic- two neuron pathway which synapses a ganglian
somatic- one long myleinated motor neuron from CNS to target cell. (direct connection)
autonomic- two neurons are preganglionic and postganglionic
somatic= heavily myleinated for fast conducion
autonomic= preganglionic= lightly myleinated
postganglionic= no mylein
structrual difference between sympathetic and parasympathetic pathways
sympathetic ganglia are closer to spinal cord whereas parasynpatheic ganglia are closer to target organ.
sympatheic have shorter preganglionic strand which is mylientaed. whereas parasympathetic have longer preganglionic strand which is mylienated.
at both synapses acetycholine is released to nicotinic receptor.
parasynpathetic release acetylcholine to muscarinic receptor to target organ e.g. heart
sympathetic mostly releases noradrenaline to adrenergic recpeptor to target organ e.g. heart
the receptors for somatic and autonomic systems
somatic = nicotinic in skeletal muscle
autonomic= nicotinic in ganglia.
muscarinic or adrenergic in target tissue
what kind of receptors are muscarinic and adrenergic receptors
G protein coupled receptors
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how the autonomic nervous system can be manipulated pharmacologically
1) muscarinic antagonist e.g. atropine
2) beta- adrenergic antagonist ( beta blockers) e.g. propranolol
3) beta- adrenergic agonists e.g. salbustamol
1) used in surgery to prevent parasympathetic reflexes when handling organs.
-also used as eye drops to dilate pupils
2) slows heart rate preventing arrhythmias
3) promotes bronchodilation to relieve asthma
what is the main neurotrasnmitter released from cholinergic neuron
and noradrenernic neuron
-aceylycholine
-noradrenaline