AVM Flashcards

(39 cards)

1
Q

What is AVM

A

Dysplastic blood vessels artery drain to vein w/o capillary, 🚫 brain 🧠 pranchyma in the nidus

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2
Q

Flow in AVM

A

Medium to high pressure
High flow

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3
Q

%%Risk of hemorrhage

A

1st time 1%/y
Recurrent 5%/y

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4
Q

Risk factor for ⬆️ AVM rupture ⭐️

A

Female , Age
Deep venous drainage
Feeding artery anurysum
Small AVM
Previous hemorrhage

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5
Q

%risk of seizure

A

1st time unrupture AVM 8%
5-y risk of epilepsy and recurrent seizure 60%

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6
Q

Source of AVM bleeding

A

Anurysum

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7
Q

SRS sterotactic surgery obligation rate

A

70-80%

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8
Q

Indication of SRS

A

Deep lesion
< 3 cm

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9
Q

Embolization indication

A

High grade S-M
High flow

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10
Q

Classification or type of AVM

A

1- parenchyma AVM. ( pial, subcortical,paraventricuLr,, combined)
2- dural AVM
3- mix prannchyma+dural AVM

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11
Q

MMC age of AVM

A

Young 30 vs 🔛 anurysum 40s

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12
Q

Syndrome asso w/ AVM ⭐️

A

Osler-Weber-Rendu syndrome (hereditary hemorrhagic telangiectasia)

Klippel-Trénaunay-Weber syndrome,
Parkes Weber syndrome,
Sturge Weber syndrome.

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13
Q

MCC presentation AVM

A

Hemorrhage [ pure IVh 🔜 paraventriculrAVM , SAH
Smallest AVM bleed more than large ⏩️ high flow and pressure ) ,)
2nd seizure
Mass effect ,
Bruit if dural
HC in ped 🔜 VOM

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14
Q

The strongest prognosticator for future hemorrhage

A

Previous hemorrhage

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15
Q

RF seizure

A

Young
Temporal
Cortical
Idus > 3
Hemorrhage

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16
Q

DX

A

CT to r/ o hemorrhage , calcification within the nidus
CTA high sensitivity and specificity
MRI ; T1, T2 GRE, SWi ( flow viod,feeding and draining hemosidrine)
🔘 edema ➡️ tumors , hemosidren ⭕️ SVM
MRA ➖ limited to detect small BV < 1 Mm , small nidus < 10 mm , anurysum
DSA ( tangle , draining and feeeding )

17
Q

Spetzler-Martin (S-M) grade of AV

A

Estimate risk of surgical resection
Requiring DSA or cross section image CT,MRI
Grade 6 untreatable
Mc grade present at stage III S-M

⭐️ Class A (S-M Grade I & II): surgical resection

● Class B (S-M Grade III): multimodality treatment

Class C (S-M Grade IV & V): f/ angiogram every 5 year if ➡️ new deficit ,steal sx,anurysum migh treat

18
Q

AVM mature at

A

At age 18 becom more compact

19
Q

Lawton-Young supplementary grading scale for AVMs

A

Better than S- M
Predict post operative surgical outcome using mRS
Use only inoperative AVM

20
Q

When can resection AVM after hemorrhage evacuation

A

2-6 week to allow ⬇️ edema and better AVM evaluation

21
Q

Mangment of rupture AVM

A

If low S- M with low L-Y , or high S- M with low L-Y
High S-M with fixed neurological deficit unlikely to affect after surgery

22
Q

Tx un rupture AVM according to ARUBA = medical > medical + intervention

23
Q

Surgical resection indication , cons , pron

A

Indication S-M 1 or 2
Cons eliminate risk of rebleeeidng and seizure controls
Cons invasive , cost 💲

24
Q

SE of SRS

A

Delay Se
Radarion necrosis🔘
🧠 edema , cystic formation
Pregnancy neurological changes

25
SRS prons vs cons
Pron+ outpatient , non invasive , no recovery preriod , gradual reeducation , seizure control - latency period take 1-3 y to respond Risk of bleeding same during latency
26
Endovascular AVM
Should done ✅ before 24-48 hr before resection Pros +facilitate surgery if size Cons- no permanent olitration , multiple procedures
27
E,bolization prior SRS rate
W/ embolization 47% W/o 70%
28
Things had to take in consideration when tx AVM
associated aneurysms: on feeding vessels, draining veins, or intranidal 2. flow: high or low 3. age of patient 4. history of previous hemorrhage 5. size and compactness of nidus 6. availability of interventional neuroradiologist 7. general medical condition of the patient
29
Surgical techniques
Wide exposure Isolate and clip A then ▶️ vein Working sulci and fissure
30
Delay complication
NBPB normal pressure breakthrough ➡️ post op hemorrhage Strok ➡️ occlusive hypermia Rebleedin Seizure
31
Follow up 🔝
If complete ✅ resection ⏩️ post op DSA or MRI then ⏩️ 1 &5 y CTA or MRA After SRS ☢️⏩️ a 6 m MRA, MRI oIF ❌🚫 CTA If obliterate bu SRS ☢️ post op DSA ( latency period )
32
📍 MCC location for AVM
parietal➡️ insula, frontal, and temporal lobe
33
📍 apex of AVM
Preiventricular
34
📍 AVM base
Cortex
35
factors AVM ➡️ spontaneous occlusion
single draining vein single feeding artery Small nidus (<3 cm
36
Factor increase ⬆️ AVM bleeding 🩸
Anatomical factor ; aneurysm , nidus( diffuse morphology ) , location ( deep preiventricular, intraventricualr, infratentorium) , impaired venous drainage ( deep venous drainage, venous stenosis, single draining vein, and venous reflux into a sinus or a deep vein), small size AVM Hemodynamic➡️ high feeding artery pressure Patient factor ➡️ increasing age, pediatric patients, pregnancy, HTN Others residual nidus S-M 4 -5
37
Factor ⬇️ AVM bleeding
Arterial stenosis 2. Arterial angioectasia 3. Arterial border zone location of brain AVMs 4. Venous recruitment
38
Theory of seizure in AVM
Low CBF ➡️ ischmic insult brain Gliosis around nidus might cause seizure
39
ARUBA inclusion and exclusion criteria ⭐️
Inclusion Criteria: Patient must have unruptured BAVM diagnosed by MRI/MRA, CTA and/or angiogram Patient must be 18 years of age or older Patient must have signed Informed Consent, Release of Medical Information, and Health Insurance Portability and Accountability Act (HIPAA/U.S. only) Forms Exclusion Criteria: Patient has BAVM presenting with evidence of recent or prior hemorrhage Patient has received prior BAVM therapy (endovascular, surgical, radiotherapy) Patient has BAVM deemed untreatable by local team, or has concomitant vascular or brain disease that interferes with/or contraindicates any interventional therapy type (stenosis/occlusion of neck artery, prior brain surgery/radiation for other reasons) Patient has baseline Rankin ≥2 Patient has concomitant disease reducing life expectancy to less than 10 years Patient has thrombocytopenia (< 100,000/μL), Patient has uncorrectable coagulopathy (INR>1.5) Patient is pregnant or lactating Patient has known allergy against iodine contrast agents Patient has multiple-foci BAVMs Patient has any form of arteriovenous or spinal fistulas Previous diagnosis of any of the following - Patient has a diagnosed Vein of Galen type malformation Patient has a diagnosed cavernous malformation Patient has a diagnosed dural arteriovenous fistula Patient has a diagnosed venous malformation Patient has a diagnosed neurocutaneous syndrome such as cerebro-retinal angiomatosis (von Hippel-Lindau), encephalo-trigeminal syndrome (Sturge-Weber), or Wyburn-Mason syndrome Patient has diagnosed BAVMs in context of moya-moya-type changes Patient has diagnosed hereditary hemorrhagic telangiectasia (Rendu-Osler-Weber)