Axon regeneration

Question 1

https://doi.org/10.1038/s41582-019-0280-3

Answer 1

• Chondroitinase ABC and anti-NogoA treatment to reduce inhibitory signalling in the neuronal extrinsic environment after spinal cord injury has promise
• Use of spinal cord derived neural stem cells and growth factors for long distance axon regeneration
• Electrical epidural stimulation and brain-machine interfaces have demonstrated impressive improvements in voluntary motor function
• Different types of neuroplasticity and regeneration: plasticity and reorganisation of injured corticospinal neurons in the cortex, sprouting of injured corticospinal axons onto spared propriospinal neurons, sprouting of uninjured popriospinal neurons, sprouting of uninjured corticospinal axons. All this happens at the same time.