B12: Homeostasis in Action Flashcards

1
Q

What is the normal human body temp?

A

37C

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2
Q

Where is the body temperature monitored?

A

By the thermoregulatory centre in the brain

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3
Q

How does the thermoregulatory centre control body temperature?

A

Contains receptors which are sensitive to the temperature of the blood. The skin also contains these receptors - they send electrical impulses down sensory neurones to the thermoregulatory centre.

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4
Q

What happens when the body temperature of a person gets too high?

A
  1. Sweat glands release sweat onto the surface of the skin, which evaporates and takes thermal energy away from the body.
  2. Flushing - under the surface of the skin, there is a network of fine blood capillaries, supplied with blood by blood vessels. These blood vessels dilate (get wider - vasodilation), therefore more blood can flow into the capillaries and heat can now transfer out of the blood
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5
Q

What happens when the temperature of a person drops too low?

A
  1. Vasoconstriction - less blood vessels flow into the capillaries and therefore less heat is transferred outside of the body
  2. Shivering - skeletal muscles contract. To generate energy for contraction, muscles increase their rate of respiration and the body warms up as heat is generated.
  3. No sweat
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6
Q

Why does the body have to maintain water levels?

A

Water moves in and out of body cells through osmosis. If blood is too dilute, water moves into cells by osmosis. If it’s too concentrated, then water moves out of the cells. If body cells gain or lose too much water by osmosis then they don’t work efficiently. Therefore, water levels must be kept constant.

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7
Q

How can water in the body be lost?

A

Exhalation
Sweat (+ sodium ions also lost)
Urine

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8
Q

Why can the body not control how much water, ions or urea is lost by sweat?

A

Sweating is part of the temperature control system

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9
Q

What happens if blood is too dilute?

A

If blood is too dilute, kidneys remove excess water, as well as urea and excess ions are removed as urine

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10
Q

Describe how the kidneys filter the blood

A

Humans have 2 kidneys. Blood enters the kidneys via arteries - this blood contains urea. The kidneys remove this, as well as excess ions and excess water; which leave the kidney as urine (stored in the bladder). Clean blood now leaves the kidney through the vein.

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11
Q

How do the kidneys adjust the levels of molecules in the blood (ultrafiltration)?

A

Blood passes through the capillaries, where small molecules are filtered out of the blood, including ions, urea and water as well as glucose. These pass into a tube. Now all of the glucose, some ions and some water is reabsorbed back into the blood (selective reabsorption). Urea, excess ions and water are released as urine.

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12
Q

How does the body deal with excess amino acids?

A

Liver breaks down excess amino acids to make ammonia (deamination). Ammonia is toxic, so the liver converts it into urea, which is safely excreted by the kidneys

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13
Q

Describe what happens to the release of ADH if the blood becomes too concentrated (water level drops)

A

Water level falls, therefore more ADH is released by the pituitary gland. It travels to the kidneys and causes the tubules to become more permeable to water (more water can pass out of the tubules), meaning more is reabsorbed from the tubules back into the blood. This means less urine is produced and the water level rises.

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14
Q

Describe what happens to the release of ADH if the blood becomes too dilute

A

Pituitary gland stops releasing ADH, meaning kidneys absorb less water into the blood and more urine is excreted.

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15
Q

What is kidney dialysis?

A

When water level, ion levels and urea need to be adjusted using a machine

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16
Q

What happens when a patient has kidney failure?

A

Their blood contains a higher conc. of water, ions and urea.

17
Q

Describe the process of kidney dialysis

A

Patient’s blood passes through a partially permeable membrane, allowing water, ions and urea through, but not larger proteins and blood cells. On the other side of the membrane a dialysis fluid is formed, containing a normal conc. of water and ions, and no urea.

18
Q

Why is the dialysis fluid constantly refreshed?

A

Ensures there is always a large conc. gradient for urea and no

19
Q

What are the disadvantages of dialysis?

A

Patients have to visit a hospital several times a week (inconvenient)
Have to control diet to avoid high levels of urea

20
Q

What is a kidney transplant?

A

A diseased kidney being replaced with a healthy kidney from a donor

21
Q

What are the disadvantages of kidney transplants?

A

Donated kidney can be rejected by the patient’s immune system

22
Q

Compare kidney dialysis to kidney transplants:

A

Dialysis - no shortage of machines/requires frequent treatments/expensive long term
Transplant - shortage of donors/ patient leads a normal life/expensive initially/patients must take anti-rejection drugs for life