B2.1 Flashcards

Membranes and Membrane Transport (32 cards)

1
Q

what macromolecules are in membranes

A

proteins
lipids
small carbs

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2
Q

what are the major classes of lipids

A

phospholipids
glycolipids
sterols

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3
Q

describe what a phospholipid looks like

A

modified glycerol molecule with a neg charged phosphate group and two fatty acid chains

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4
Q

describe phospholipids in an aqueous environment

A

tails point inward

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5
Q

where is cholesterol located

A

between tails

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6
Q

term for water loving and hating

A

amphipathic

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7
Q

what can pass through the membrane

A

steroids
lipid soluble
small uncharged (h20, o2)

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8
Q

what is permability reliant on

A

hydrophobic/hydrophilic nature

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9
Q

what is simple diffusion + example

A

the passive transport of molecules from high to low concentration
diffusion of oxygen from high to low concentration in red blood cells

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10
Q

what is a transmembrane protein

A

a protein that extends fully across a membrane (integral)

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11
Q

explain the polarity of integral proteins

A

top/outer part is hydrophilic and interacts with the heads, while the inner part is hydrophobic and interacts with the tails

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12
Q

explain the polarity of peripheral proteins

A

hydrophilic and interacts with the heads

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13
Q

4 functions of membrane proteins

A

cell - cell recognition
transport
receptors
enzymes

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14
Q

function of transport proteins + 2 types

A

facilitate movement
channel proteins
- form channels for movement
carrier proteins
- conformational change

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15
Q

function of recognition proteins

A

distinguish between self and non self cells with cell - cell recognition

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16
Q

function of receptor proteins

A

binding of molecules to this protein can facilitate reactions or processes

17
Q

function of enzyme proteins

A

catalyze reactions

18
Q

what are aquaporins

A

integral proteins that speed up the movement of water down a concentration gradient

19
Q

Facilitated diffusion

A

movement of solutes down a concentration gradient monitored by size and polarity
movement is mediated by size and polarity
aided by channel and carrier proteins

20
Q

what type of protein is used for ion pumps

A

channel proteins

21
Q

what decides the ion used for the channel protein

A

binding sites being highly specific

22
Q

what forms of stimuli can open/close

A

changes in voltage
binding of molecules (ligand gated)

23
Q

how do carrier proteins transfer molecules

A

undergo conformational change and binds to the solute

24
Q

what is active transport used for

A

transporting nutrients against a concentration gradient
remove waste
maintain concentrations

25
two types of active transport
direct --> regular, uses atp indirect --> movement of one down its gradient makes another against its gradient
26
two classes of recognition proteins
gated ion channels specific carrier proteins (GLUT)
27
types of glycolipids
glycoglycerolipids --> based on glycerol molecules glycophingolipids --> derivatives of sphingosine
28
how do glycolipids contribute to membrane stability
forms h bonds with mobile water
29
functions of glycolipids and glycoproteins
cell - cell recognition cell adhesion cell signalling
30
what is glycocalyx
sticky layer formed by surface of glycolipids and glycoproteins
31
what contributes to the fluid mosaic model
lipids and proteins can move freely in the membrane
32