B5 mAbs

Question 1

What is a mAbs

Answer 1

An antibody produced from a single clone of B cells that is specific to one type of antigen

Question 2

Use of mAbs in Therapeutics

Answer 2

Deliver drugs to cancer cells

Bind to receptors on cancer cells to stop molecules that cause cell division from binding

Question 3

use of mAbs in diagnostics

Answer 3

Molecules bind to mAbs, formation of antibody antigen complexes can be detected

Question 4

Ethical issues of mAbs

Answer 4

Use of human trials
Injecting mice to produce them

Question 5

Step 1 of the ELISA Test

Answer 5

Complementary Antibodies are bound to a reaction vessel

Question 6

Complementary Antibodies are bound to a reaction vessel

Step 2

Answer 6

Patient sample is added, target antigens bins to antibody

Question 7

Patient sample is added, target antigens bins to antibody

Step 3

Answer 7

Sample is washed,
Second complementary antibody with enzyme attached is added

Question 8

Sample is washed,
Second complementary antibody with enzyme attached is added

Step 4

Answer 8

Sample is washed
Substrate is added and reacts with enzyme to form a colour change