B8-040 Benign Prostatic Hyperplasia Flashcards

1
Q

most common cause of post-TURP hyponatremia

A

dilutional

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2
Q

what medications reduce the need for BPH related surgery?

A

5-a-reductase inhibitors (finasteride)

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3
Q

what is the best indication for treatment of BPH symptoms?

A

degree of bother

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4
Q

most common location of prostate cancer

A

peripheral zone

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5
Q

most common location of BPH

A

transition zone

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6
Q

[…] cancer in the mother is a risk factor for prostate cancer

A

breast

(BRCA2)

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7
Q

describe what’s going on in these uroflowmetry graphs

A

a. normal male
b. normal female
c. and d. intermittent flow
e. prolonged weak stream

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8
Q

[…] inhibition leads to prostatic relaxation

A

a1

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9
Q

block the conversion of T to DHT

A

5a reductase

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10
Q

older a1 blockers can cause […]

A

orthostatic hypotension

(doxazosin/terazosin, but cheap)

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11
Q

which a1 blocker has to lowest rate of retrograde ejaculation?

A

alfuzosin

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12
Q

what medication is able to reduce prostate volume up to 20%?

(show to reduce need for surgery)

A

5a reductase inhibitors

(finasteride- type 2, dutasteride type 1 and 2)
(du=dual)

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13
Q

NOS mediated smooth muscle relaxation

A

PDE5 inhibitors

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14
Q

used to relieve irritative symptoms [2]

A

anticholinergics (oxybutynin)
beta 3 agonists (mirabegron)

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15
Q

AUA recommends […] for prostate cancer screening in men ages 55-70

A

shared decision making

(1-2 year intervals)

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16
Q

water vapor therapy that uses steam to destroy adenoma

A

rezum

17
Q

staple-like implants that hold the prostatic lobes apart

A

urolift

18
Q

non-surgical, minimally invasive surgical options [2]

A

rezum
urolift

19
Q

historical gold standard prostate surgery

A

TURP

20
Q

benefits of laser ablation over TURP

A

less blood loss
shorter catheterization
outpatient

21
Q

disadvantage of laser ablation over TURP

A

no tissue for pathology

22
Q

surgical technique that has supplanted open surgery removal for very large glands

A

laser enucleation

23
Q

laser goes between the prostate capsule and adenoma

tissue then morcellated and pulled out in pieces for pathology

A

laser enucleation

(great for very big glands)