B8.067 Decision Making in the Newborn Flashcards

(46 cards)

1
Q

neonatal dilemmas by frequency

A
  1. rashes
  2. jaundice
  3. early discharge
  4. hypoglycemia
  5. tachypnea
  6. DDH
  7. sepsis (GBS)
  8. failure to stool/ urinate
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2
Q

what is a late preterm infant

A

birth between 34 and 36w6d gestation

often the size and weight of term infants

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3
Q

the “problem” with late, preterm infants

A

treatment by caregivers and parents as if they are developmentally mature
evidence indicates higher risk of mortality and morbidity and hospital readmissions

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4
Q

what types of issues are late preterm infants more at risk for?

A
airway instability
apnea and bradycardia
excessive sleepiness
excessive weight loss
feeding intolerance
hyperbilirubinemia
hypoglycemia
hypothermia
immature self regulation
respiratory distress
sepsis
weak suck
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5
Q

what should be the first step if a neonate appears jaundiced?

A

order a serum bilirubin

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6
Q

function of phototherapy

A

converts bilirubin into a soluble form for excretion

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7
Q

at what serum bili level is jaundice appreciated visually

A

around 5 mg/dl

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8
Q

at what stage of life is jaundice ALWAYS pathologic

A

<24 hours old

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9
Q

how is risk of kernicterus assessed

A

age in hours compared to serum bili level
options:
-phototherapy
-exchange transfusion

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10
Q

root causes of kernicterus

A

early discharge (<48 hr) with no early follow up, esp in late pre term infants
failure to check bili in infants noted to be jaundiced in first day of life
failure to recognize risk factors for jaundice
underestimating severity of jaundice by visual assessment
lack of concern
delay in measurement of bili or initiation of phototherapy
failure to respond to parental concern

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11
Q

obstetrical risk factors for nonhemolytic hyperbilirubinemia

A
previously jaundiced sibling
east asian race
infant of a diabetic mother
bruising, cephalohematoma, vacuum extraction (due to breakdown of Hgb)
<37 weeks gestation
maternal age > 24
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12
Q

neonatal risk factors for nonhemolytic hyperbilirubinemia

A
breast feeding
male
caloric deprivation- weight loss > 25%
jaundice before discharge
increased hemolysis
crigler-najjar
hospital stay <72 hrs
bilirubin >75% for age
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13
Q

what is the bhutani nomogram

A

plots age vs serum bilirubin to stratify risk of significant hyperbilirubinemia requiring intervention

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14
Q

what can WE do to prevent kernicterus

A

dont ignore visible jaundice on first day
check curves for risk
check levels
follow babies discharged in <72 hrs in 24-48 hrs
dont ignore phone calls
don’t delay treatments

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15
Q

maternal risk factors of GBS

A

positive maternal GBS culture of vagina or rectum
previous infant who had invasive GBS disease
GBS bacteriuria during this pregnancy
delivery at <37 wks
intrapartum fever (>38)
rupture of membranes >18 hrs

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16
Q

full GBS evaluation

A
CBC w diff
blood culture
chest Xray
lumbar puncture
treat
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17
Q

limited GBS evaluation

A

CBC w diff
blood culture
observe >48 hr

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18
Q

when do you do a full GBS eval

A

signs of neonatal sepsis!!!

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19
Q

when do you do a limited GBS eval

A

maternal chorioamionitis
OR
if mother should have received GBS prophylaxis and didnt + neonate is <37 wks and membrane rupture was > 18 hrs

20
Q

when do you observe for >48 hrs due to GBS risk

A

if GBS prophylaxis is indicated for the mother AND it was received properly
OR it wasn’t received but the baby is >37 weeks and membrane rupture was < 18 hrs

21
Q

what is GBS prophylaxis for a mother

A

IV penicillin, ampicillin, or cefazolin for >4 hrs before delivery

22
Q

goals of treatment of hypoglycemia in newborn

A

normalize blood glucose rapidly

maintain blood glucose until normal homeostasis is established

23
Q

normal treatment of newborn hypoglycemia

A

enteral feedings
-if baby is term, asymptomatic, and has a good suck
use formula or breast milk (D20)
if next glucose level is <40, enteral feeding should be considered unsuccessful > go to IV

24
Q

IV treatment of newborn hypoglycemia

A
bolus 2cc/kg D10W (highest level IV can go)
continuous infusion
baseline: 4-8 mg/kg/min
100 cc/kg/day of D5W
check glucose at 30, 60, and 120 min
25
follow up on treatment of hypoglycemia
if preprandial glucose > 50 for 12-24 hrs, start to wean decrease infusion rate by 10-20% if weaning not possible, look for persistent problem
26
groups of risk factors for hypoglycemia
1. limited glycogen 2. hyperinsulinism 3. unknown - large for gestational age - sepsis - polycythemia
27
reasons for limited glycogen in newborn
small for gestational age prematurity birth stress glycogen storage diseases
28
reasons for hyperinsulinism in newborn
``` infant of a diabetic mother beckwith-wiedemann nesidoblastosis pancreatic adenoma Rh disease exchange transfusion drugs urinary catheters ```
29
what is neonatal abstinence syndrome
a group of problems that occur in a newborn who was exposed to addictive opiate drugs while in the mother's womb
30
classic triad of NAS
high pitched cry tremor tachypnea
31
screening for NAS
maternal history maternal urine drug screen infant drug screen - can have false negative as it requires recent exposure to be accurate meconium testing - often not available and not practical as it delays diagnosis
32
neuro symptoms of NAS
``` excessive irritiability hyper reflexive decreased sleep increased muscle tone tremors myoclonic jerks seizures ```
33
GI symptoms of NAS
diarrhea regurgitation poor suckling
34
autonomic symptoms of NAS
diaphoresis temp instability sneezing mottling
35
nonpharmacologic treatments for NAS
soothing techniques: swaddling, pacifier, rocking environment modification (quiet, dark rooms) maternal education and reassurance -babies cry for numerous reasons -maternal guilt -psych and rehab services for mother 60-80% of infants won't respond to non-pharma and will need pharma therapy
36
goal of pharmacotherapy in NAS
relief of signs, such as seizures, weight loss, sufficient to allow parental care of infant no national standardized guidelines treatment options vary depending on maternal drug exposure
37
pharmacotherapy options on NAS
typically, opiates used for opioid exposed infants may use 2nd line agents as needed may consider other treatment options if polysubstance use
38
what is developmental dysplasia of the hip
spectrum of disorders affecting the acetabulum and the proximal femur dynamic condition, can occur -prenatally -postnatally
39
continuum of pathology/outcomes of developmental dysplasia of the hip
stabilize and become normal stabilize and remain dysplastic progress to dislocation
40
DDH statistics
``` subluxable hips (14/1000) dislocatable hips (2.5/1000) dislocated hips (1.3/1000) ```
41
incidence of DDH
``` varies by race M:F = 1:6 left =60%, right =20%, bilateral =20% multifactorial breech has up to 23% incidence ```
42
impact on fam history on DDH
6% with affected sib 12% with affected parent 36% with affected parent and sib
43
most reliable screening for DDH
physical exam
44
physical exam for DDH
child should be warm and relaxed barlow test and ortolani sign good in first 2 months -barlow attempts to dislocate an unstable hip (applies adduction and posterior pressure) -ortolani sign attempts to relocate (applies abduction and anterior pressure on knee) click = innocent soft tissue sign clunk = bad
45
presentation of DDT after 2 months of age
``` barlow and ortolani are of limited value at this stage limitation of abduction asymmetric skin folds uneven knee heights bilateral dislocations can be misleading ```
46
when should you use an US for DDT eval?
after 2 months | better than xray until 6 months