Strep General: - Structure? - Aerobic? - Growth? - Catalase? - Fermenter?

- Gram (+) Cocci - Microaerobic - Linear - Negative - Yes

Group A Strep: - Name? Hemolytic? Lancefield? Bacitracin? - 2 cell wall proteins? Function? - 4 Enzymes? - 4 primary infection processes? - 2 post strep sequelae? - Treatment?

- Strep pyrogenes; B; A; sensitive - C/M (main virulence; precent phago/inhibits complement) - Strep O/ Strep S/ Pyrogenic Exotoxin/ Streptokinase 1. ) Pharyngitis (strawberry tongue) 2.) Skin infection (many including Fourniers Gangrene) 3.) Scarlet Fever (spares face) 4.) TSST = Exotoxin A binds MHC2 (IL2/INFg) 1. ) Rheumatic Fever (JONES criteria = Joints, heart, nodules, EM, Cholera) 2.) PSGN one week later - Pen G

Group B Strep: - Hemolytic? Aerobic? Bacitracin? - Carried where? - In neonates? (3) - Hippurate test? - Treatment?

- B; Fac. Anaerobe; Resistant - 25% vagina - Meningitis, Pneumonia, Sepsis - + - Pen G

Viridans Strep: - Hemolytic? Aerobic? - Dental caries version? - Optochin? - EC dextran effect? - 3 pathologies? - Treatment?

- a; faculative anaerobe - S. Mutans - Resistant - Attach to damaged heart - Subacute endocarditis, dental carries, brain/liver abscess - Pen G

Group D strep: - 2 types? - Hemolytic? Aerobic? Protein? - 3 pathologies? - Worry with VRE? - Treatment?

- Enterococci/ non (Bovis --> Colon Cancer) - Gamma, faculative anaerobe, Dextran - Subacute endocarditis, billiary tract infections, nocosmial UTI - Give to S. Auerus - Ampicillin

Strep Pneu: - Hemolytic? Aerobic? - Optochin? Quelleng test? - Major virulence? - Pneumo warrior has? (3) - Treatment?

- a hemolytic; fac. anaerobe - optochin sensitive; positive - IgA protease - Lung, ear, head - IM Pen G

Staphylcoccus General: - Shape? - Catalase? - Growth?

- Gram + Cocci - positive - Clusters

Staph Aureus: - Coagulase? Does what? Aerobic? - Virulence? - 3 Enzymes? Protein? 1. ) Inflammatory Dz? (5) 2. ) Toxin Mediated? (3) - MRSA has chrom DNA segment called? Does what? - Treatment? - MRSA treatment?

- Positive; creates fibrin clot; faculative anaerobe - Protein A = Binds Fc of IgG - Hemosylins, Leukocidins (PVL form absess), Penicillinase, Novel binding protein 1. ) Skin infection, organ abscess, post flu pneumonia, endocarditis, osteomyelitis 2. ) TSST, Scalded skin, Rapid onset gastro (mayo) - mecA, new binding protein - 1st gen ceph, Clinda - Vanco

Staph Epidermidis: - Coag? Common on? Create a what? - Treatment?

- negative, foley catheters/prosthetics; biofilm - Vanco

Enteric Bacteria General: - Non-fermenters? (3) - Invade lymph? (3) - O antigen is? - K? - H?

- Salmonella, Shigella, Pseudonomas - Salmonella Typhi, Yersernia, Campylobacter - LPS - Capsule - Motile

E. Coli: - Structure? Fermenter? Hemolytic? - 3 virulence factors? Causes what? 1. ) ETEC: AKA? Invasion/inflame? 2 toxins? Like what? - Effects where? Treatment? 2. ) EHEC: Toxin? Causes? (Triad) - Invasive? Does not ferment what? Treatment? 3. ) EIEC: Invades what? (2) Causes? 4. ) EPEC: Invasive? Toxin? Causes?

- GNR, yes, Beta 1. ) Fimbiae (Cystitis/pylo) 2.) LPS (sepsis) 3.) K Capsule (pneumonia/neonatal meningitis) 1. ) Travellers; none; Heat stable/labile; Cholera; small bowell; FQ 2. ) Shiga like toxin; thrombocytopenia, microthrombi (anemia), HUS - No, sorbitol, Supportive 3. ) Mucosa/epi; shiga like inflammation 4. ) No, No, malabsorption in kids

Klebsiella Pneumonia: - O anitgen? Structure? Found where? - Causes what? (4) - Effects who? (3) - Sputum?

- Yes but no H/K; GNR of gut/hospitals - Lobar pneumonia, sepsis, foleys, UTI's - DM, alcoholics, Hospital ITI - Red currant

Proteus: - Structure? - Oxidase? Lactose? - Urea? - Common cause of? Urine?

- GNR - Negative, non fermenter - Splitting - Hospital UTI, alkaline

Bacterial Bugs Flashcards by Ben Leon

Strep General:

Structure?
Aerobic?
Growth?
Catalase?
Fermenter?

Gram (+) Cocci
Microaerobic
Linear
Negative
Yes

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Group A Strep:

Name? Hemolytic? Lancefield? Bacitracin?
2 cell wall proteins? Function?
4 Enzymes?
4 primary infection processes?
2 post strep sequelae?
Treatment?

Strep pyrogenes; B; A; sensitive
C/M (main virulence; precent phago/inhibits complement)
Strep O/ Strep S/ Pyrogenic Exotoxin/ Streptokinase
1. ) Pharyngitis (strawberry tongue) 2.) Skin infection (many including Fourniers Gangrene) 3.) Scarlet Fever (spares face) 4.) TSST = Exotoxin A binds MHC2 (IL2/INFg)
1. ) Rheumatic Fever (JONES criteria = Joints, heart, nodules, EM, Cholera) 2.) PSGN one week later
Pen G

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Group B Strep:

Hemolytic? Aerobic? Bacitracin?
Carried where?
In neonates? (3)
Hippurate test?
Treatment?

B; Fac. Anaerobe; Resistant
25% vagina
Meningitis, Pneumonia, Sepsis
+
Pen G

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Viridans Strep:

Hemolytic? Aerobic?
Dental caries version?
Optochin?
EC dextran effect?
3 pathologies?
Treatment?

a; faculative anaerobe
S. Mutans
Resistant
Attach to damaged heart
Subacute endocarditis, dental carries, brain/liver abscess
Pen G

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Group D strep:

2 types?
Hemolytic? Aerobic? Protein?
3 pathologies?
Worry with VRE?
Treatment?

Enterococci/ non (Bovis –> Colon Cancer)
Gamma, faculative anaerobe, Dextran
Subacute endocarditis, billiary tract infections, nocosmial UTI
Give to S. Auerus
Ampicillin

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Strep Pneu:

Hemolytic? Aerobic?
Optochin? Quelleng test?
Major virulence?
Pneumo warrior has? (3)
Treatment?

a hemolytic; fac. anaerobe
optochin sensitive; positive
IgA protease
Lung, ear, head
IM Pen G

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Staphylcoccus General:

Shape?
Catalase?
Growth?

Gram + Cocci
positive
Clusters

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Staph Aureus:

Coagulase? Does what? Aerobic?
Virulence?
3 Enzymes? Protein?
1. ) Inflammatory Dz? (5)
2. ) Toxin Mediated? (3)
MRSA has chrom DNA segment called? Does what?
Treatment?
MRSA treatment?

Positive; creates fibrin clot; faculative anaerobe
Protein A = Binds Fc of IgG
Hemosylins, Leukocidins (PVL form absess), Penicillinase, Novel binding protein
1. ) Skin infection, organ abscess, post flu pneumonia, endocarditis, osteomyelitis
2. ) TSST, Scalded skin, Rapid onset gastro (mayo)
mecA, new binding protein
1st gen ceph, Clinda
Vanco

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Staph Epidermidis:

Coag? Common on? Create a what?
Treatment?

negative, foley catheters/prosthetics; biofilm

- Vanco

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Staph Saprophyticus:

Coag?
Common cause of?

negative

- UTI

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Enteric Bacteria General:

Non-fermenters? (3)
Invade lymph? (3)
O antigen is?
K?
H?

Salmonella, Shigella, Pseudonomas
Salmonella Typhi, Yersernia, Campylobacter
LPS
Capsule
Motile

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E. Coli:

Structure? Fermenter? Hemolytic?
3 virulence factors? Causes what?
1. ) ETEC: AKA? Invasion/inflame? 2 toxins? Like what?
Effects where? Treatment?
2. ) EHEC: Toxin? Causes? (Triad)
Invasive? Does not ferment what? Treatment?
3. ) EIEC: Invades what? (2) Causes?
4. ) EPEC: Invasive? Toxin? Causes?

GNR, yes, Beta
1. ) Fimbiae (Cystitis/pylo) 2.) LPS (sepsis) 3.) K Capsule (pneumonia/neonatal meningitis)
1. ) Travellers; none; Heat stable/labile; Cholera; small bowell; FQ
2. ) Shiga like toxin; thrombocytopenia, microthrombi (anemia), HUS
No, sorbitol, Supportive
3. ) Mucosa/epi; shiga like inflammation
4. ) No, No, malabsorption in kids

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Klebsiella Pneumonia:

O anitgen? Structure? Found where?
Causes what? (4)
Effects who? (3)
Sputum?

Yes but no H/K; GNR of gut/hospitals
Lobar pneumonia, sepsis, foleys, UTI’s
DM, alcoholics, Hospital ITI
Red currant

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Proteus:

Structure?
Oxidase? Lactose?
Urea?
Common cause of? Urine?

GNR
Negative, non fermenter
Splitting
Hospital UTI, alkaline

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Enterobacter:

Structure?
Motile?
Lactose?

GNR
Very
Fermenter

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Serratia:
Structure? Lactose?
Causes? (2)
Unique how?

GNR, slow fermenter
UTI/pneumonia
Bright red spot

Shigella:

Structure? Lactose? Oxidase? Motile?
Spread via? Only in?
Hydrogen sulfide? Invades mucosa causing?
Toxin? Does what?
Invades where? Apoptosis of?
Need much for infection?
Treatment?

GNR, non-fermenter; negative; no
Hematogenous, humans
None; High PMN’s
Shiga Toxin A/B = 60s ribosome
M cells on peyers patches; Macs
No
Ceftriaxone/ FG’s

Salmonella:

Fermenter? Motile? H2S?
Invades? Response?
Carried by? Virulance patho islands allow what?
Treatment?
Typhi: Only in? Sign on abdomen?
Stays where? Invades what?
No spleen cause of?
Treatment?

Non fermenter; yes; yes
Mucosa, Monocytic
Animals (turtles); Invade/survive in macs
NONE
Humans, rose spots
Gall bladder, regional lymph nodes
Osteomylitis
Ciprofloxacin/ ceftriaxone

Yersernia:

Structure? Motile? Fermenter? Oxidase?
Often found on? (2)
Invasive? Mimics? Enterotoxin?

GNR, motile, non, negative
Pet feces/ contaminated milk
Yes; crohns; yes

Cholera:
Structure? Motile? Oxidase?
Enterotoxin causes? 2 sub units?
Grows in what environment?
Common in what food?
Need what 2 things to be virulent?
Treatment?

Curved GNR; yes single flagellum; positive
Permanent Gs –> increase cAMP; Action/Binding (A/B)
Alkaline
Shellfish
Pili, cholera toxin
Supportive/ Doxy

Campylobacter:

Structure? Grows at? Oxidase? Shape?
Aerobic? Effects what part of the gut?
Found in what sources? (3)
Can cause what after infection? (2)
Treatment?

GNR; 42 degrees C; positive; wing
Micro; Distal illeum
Pets, poultry, unpasteurized milk
Guillen Barre, Reactive arthritis
Erythromycin

H. Pylori:

Invasive? Aerobic? Urease? Oxidase?
Common cause of?
Treatment?

Non; micro; positive; positive
Duo ulcers
PPI + Azithro + Metro/Amox

Chlamydia:

Structure? Obligate? ATP/ADP what?
Visualized via what stain?
Invades what type of cells?
Life cycle? (2)
C. Pneu/ C Sittaci causes?
C. Trachoma causes? (5) Also linked with? (2)
Types ABC? Types D-K? Types L1-L3?
3-5x increase risk of? Cultures? Serology?
Treatment?

Gram (-) cocci; IC; trans-locator
Geisma
Columnar epithelium
Elementary (EC); Initial body (Inhibits phagolysosome)
Atypical pneumonia
Reactive arthritis, Conjuctivitis, urethritis, PID, Lymphagonum venereum; Alzheimers/ Ht. Dz
Chronic infection/blindness; urethritis, neonatal pneumona, PID; Lympho Venereum
HIV; Specific, sensitive
Amoxocillin

Neisseria General:

Shape? Often IC of? Virulance?
Aerobic?

Gram (-) diplococci; neutrophils; IgA protease

- Strictly aerobic

Neisseria Meningitidis: - Ferments? (2) Virulence? - LPS? IgA protease? Pili? - Transmitted via? - Causes what? (2) - Media? - Prophylactic treatment? - Treatment?

- Maltose/glucose; polysacc capsule - yes; yes; yes - oral secretions - Meningitis/ W-F syndrome - Thayer-Martin VCN - Ceftriaxone - Pen G/ Ceftriaxone

Neisseria Gonorrheae: - Capsule? Ferments only? - Pili? Opa proteins? Outer membrane porins? - Causes? (6) - Systemic disease? (2) - Neonatal what? - 3 tests? Only effects? - Treatment?

- No; glucose - yes; yes; yes - uterthritis, PID, prostatitis, endoemtriosis, oophoritis, Fitz-Hugh Curtis - Sepsis, Reactive Arthritis - Ophthalmia neonatarum - Thayer, Chocolate, Transflow with CO2 - Ceftriaxone IM and 1 Amoxicillin

Trepenoma Pallidum: - AKA? Structure? - 2 motile parts? 1. ) Primary: Causes? Possible lymph node? - Test? Serology? Treatment? 2. ) Secondary: Rash on? Condyloma Latum? - Systemic dz? 3. ) Latent: % relpase? % continue on? Serology? 4. ) Tertiary: 4 effects? VDRL/PRP test? - Effects posterior column leading to? (2) 5. ) Congenital: 5 effects? Cross placenta? - Overall treatment? Jarish Herxheimer?

- Syphillis; Gram - spirochite - Axial filaments, periplasmic flagella 1. ) Painless chancre; yes - Darkfield microscopy, negative, Pen G 2. ) Hands/soles; wart like lesions - Any organ 3. ) 25%; 30%; positive 4. ) Gummas, aortitis, Argyll Robertson Pupil, Neurosyph - Weakened reflexes, no pain/temp - Saber shins, Hutchinsons Teeth, C8 deaf, saddle nose, mulberry molars, yes - Pen G/ Doxy; 50% get post AB shakes, fever, nausea