Bacterial Meningitis Flashcards Preview

Neuro Block 2 > Bacterial Meningitis > Flashcards

Flashcards in Bacterial Meningitis Deck (26):
1

causative agents for meningitis in kids younger than 3 mos

enteric, GBS, Listerial
LEG

2

causative agents for meningitis in kids 3 mos to 2 years

H flu!!, N. meningitides, strep pneumo

3

causative agents for meningitis in kids 2 - 11 years

strep pneumo and N. meningitides

4

strep pneumo vaccine effective in young kids

13 capsule = prevnar

5

structure of N. meningitides

gram - kidney bean

6

4 main virulence factors for N. meningitides

pilli, capsule, LPS, antigenic phase varient for capsule

7

reservior for N. meningitides

nasopharynx of humans

8

endemic N. meningitides strains in US

B and C

9

epidemic N. meningitides straind

A and C

10

causes rash in meningococcal dz

endotoxin = lipooligiosaccharide

11

cause of death in meningococcemia

pulm insufficiency

12

treatment for acute N. meningitides dz and prophylaxis

acute = pen, cefotxime and ceftriaxone
prophylaxis = cipro

13

diff between Manactra and Menomune

both vaccines for N. meningitides
Menomune id unconjugated and therefore has NO memory component

Manactra is conjugated to diptheria toxin = memory

14

what N. meningitides strain is NOT protected by vaccines

B

15

how is N. meningitides transmitted

saliva

16

structure of H flu

small gram - rod NON-motile

17

special growth medium for H flu

CAP (will not grow on BAP) bc needs factors X and V

18

reservoir for H flu

humans

19

distinguishing factor that allows certain strains of H flu to causes systemic dz

capsule = type b and f

20

dz caused by encapsulated vs non-encapsulated strains of H flu

encapsulated = meningitis, epiglottits, arthritis, cellulitis, osteo

non-encapsulated = otitis media, respiratory dz, conjunctivis

21

Vaccine for H flu?

yes, conjugated to diptheria toxin but only b

22

structure od listeria monocytogenes

club shaped gram + rod

23

listeria monocytogenes intracellular or extracelluar parasite

intracell

24

what cells do listeria infect

mucosal epithelial and non-immune macrophages/monocytes

25

source of listeria monocytogenes infections

Food--unpasteruized soft cheeses, hot dogs, and deli meat

26

emperic treatment for otherwise healthy indiv with suspected bacterial meningitis

3rd gen cephlasporin (ceftriaxone)
ampicillin (if listeria suspected)
vanc (if resistant S. pneumo suspected)

+/- dexamethisone