Barrett's Oesophagus

Question 1

What is Barrett’s Oesophagus?

Answer 1

Replacement of stratifies squamous epithelium by columnar epithelium in the oesophagus

Question 2

What are the causes of Barrett’s Oesophagus?

Answer 2

Persistent reflux of acid or bile
Expansion of columnar epithelium fro gastric glands or from submucosal glands
Differentiation from oesophageal stem cells
Protective responce

Question 3

What is a macroscopic sign of Barrett’s Oesophagus?

Answer 3

Red velvety mucosa in the lower oesophagus

Question 4

What is a microscopic sign of barrett’s oesophagus?

Answer 4

Columnar liner mucosa with intestinal metaplasia

Question 5

What is Barrett’s Oesophagus a risk factor for?

Answer 5

It is a premalignant condition causing an increased risk of developing dysplasia and carcinoma of the oesophagus