Peptic Ulcers Flashcards

1
Q

What is peptic ulceration?

A

A breach in the GI mucosa as a result of acid and pepsin attack. It is a special type of gastric inflammatory disease

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2
Q

What are the common sites of chronic peptic ulcers?

A

1st part of duodenum
Stomach
Oesophago-gastric junction
Stomal ulcers

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3
Q

What is stomal ulceration?

A

This is when there is failure pf a previous gastric operation to control peptic ulcer disease

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4
Q

What is the microscopic appearance of peptic ulcers?

A

Layered appearance
Floor of necrotic fibrinopurulent debris
Base of inflamed granulation tissue
Deepest layer is fibrotic scar tissue

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5
Q

What are the complications of peptic ulcers?

A
Perforation
Penetration
Haemorrhage
Stenosis
Intractable
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